Words similar to postmitotic
Example sentences for: postmitotic
How can you use “postmitotic” in a sentence? Here are some example sentences to help you improve your vocabulary:
This finding underscores the versatility of PEI as a method for introducing genes into postmitotic populations of cells, particularly as our previous efforts to transfect sympathetic neurons using lipid-based reagents (Lipofectamine and Lipofectin) had been unsuccessful.
This may reflect androgen activity in restoring the glandular structure by promoting postmitotic differentiation [ 48 49 ] . Consistent with this view, androgen administration to intact rats resulted in suppression of prostate epithelial cell proliferation and maintenance of morphological gland integrity [ 50 ] . Based on these findings, we propose that the effects of high doses of androgens on SKP2 and p27 in LNCaP cells described here reflect a differentiation and consolidation effect in vitro . If this is the case, LNCaP cells, despite being highly aneuploid derivatives of a metastatic lesion of an advanced cancer [ 39 ] , may have retained some aspects of the normal biphasic mechanism of androgen control observed in castrated rodents.
Thus in our transgenic animals, aberrant Wnt activation appears to be limited to mature, postmitotic neurons.
In this report, we describe the application of PEI in the transfection of postmitotic rat sympathetic neurons in serum-free, glia-free conditions, thereby showing the capability of PEI as a method for studying the effects of targeted genetic manipulation in a rigorously defined cell culture system.
Transfection conditions were optimized using cultures of postmitotic sympathetic neurons that had been treated with a DNA synthesis inhibitor to remove nonneuronal cells.
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