Words similar to pore
Example sentences for: pore
How can you use “pore” in a sentence? Here are some example sentences to help you improve your vocabulary:
Backbone oxygens from all four subunits of the latter portion of P form a series of K +binding sites and thus determine the selectivity of the pore.
The bacterial K +channel KcsA, whose X-ray crystal structure has been solved and is definitively a tetramer [ 30 ] , runs as a tetramer on SDS gels [ 31 ] . Furthermore, mutations that disrupt a known intersubunit interface at the level of the pore disrupt this biochemical tetramerization.
Unlike other K +-channel types, for which amino and carboxyl termini are highly variable, KQT channel sequences are even more highly conserved in some regions of the cytoplasmic carboxy-terminal region than in the conserved pore region.
Water permeability was measured as the net fluid movement driven by an osmotic gradient across intact monolayers of adenovirus-infected MDCK cells, by methods similar to those reported previously [ 27 29 ] . Cells were seeded onto Transwell filters (Costar, 1 cm 2, 0.4 μm pore size) at a density of 1.5 × 10 5cells per well.
Thus we are certain that the EC coupling expressed by fs-α 1S is mechanistically similar to control skeletal-type EC coupling but limited in magnitude by a comparatively lower density of functional DHPRs that are assembled in cells expressing fs-α 1S . It is conceivable that the functional integrity of the fragmented α 1S protein is maintained in part by the β subunit of the DHPR which spans both halves of the α1 pore subunit by binding to the I-II loop and the C-terminus [ 35 36 ] . Consistent with this explanation, we failed to detect EC coupling recovery when fs-α 1S was expressed in β1-null myotubes.
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