Example sentences for: polymerases

How can you use “polymerases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • While all bacteria, archaea and eukaryotes encode orthologs of at least four distinct subunits of DDRP, the divergent RNA polymerases of baculoviruses and yeast killer plasmids and the Corynebacterium Cgl1702 protein only contain counterparts to the β and β' subunits.

  • However, the DPBB from the RNA polymerases of yeast killer plasmids and the divergent predicted corynebacterial polymerase Cgl1702 also lack this insert (Fig.

  • This generates the necessary 3' hydroxyl group for DNA polymerases (pol β, δ or ε, in eukaryotes) to insert the correct nucleotide in later steps in the base excision repair pathway (BER-pathway) [ 7 8 ] . Recent crystal structures of huAPE1 complexed with DNA containing an abasic site [ 9 10 11 ] , combined with sequence analysis and site-directed mutagenesis, have defined the residues that participate in metal ion based cleavage of the phosphate backbone of the DNA [ 12 13 14 15 16 17 ] .

  • We postulate that these enzymes are likely to chelate 2 divalent cations and are likely follow a bimetal reaction mechanism similar to what has been proposed for nucleotide cyclases, nucleic acid polymerases, or certain phosphoesterases such as those of the HD and DHH superfamilies.

  • Despite the basic biochemical similarity among all RNA polymerases, sequence and structure comparisons indicate that these enzymes belong to at least five evolutionarily unrelated folds.


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