Example sentences for: pma-induced

How can you use “pma-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Since K ATP plays a crucial role in glucose-stimulated insulin secretion, PMA-induced hyperpolarization could be mediated by changes in K ATP activity.

  • The enhancement of K ATP activity by reducing sensitivity of K ATP to ATP seems to underlie the PMA-induced impairment of β-cells electrical excitation in response to glucose stimulation.

  • In this regard, the present findings support the idea derived from previous findings on mouse [ 15 ] or obese-hyperglycaemic mouse β-cells [ 16 ] . However, PMA-induced PKC-independent hyperpolarization of β-cells was not previously reported [ 15 16 ] . The reason for the discrepancy is not clear at the moment.

  • This inhibitory effect by PMA appeared to be independent of PKC since addition of the PKC blocker, BIM (1 μM) did not prevent PMA-induced inhibition (Fig.

  • Reduction of sensitivity of K ATP to ATP seems to underlie the PMA-induced impairment of β-cells electrical excitation in response to glucose stimulation.


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