Example sentences for: platelet

How can you use “platelet” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • One GPIbα polymorphism is referred to as "VNTR" because it consists of a variable number of tandem repeats of 39 base pairs, each repeat leading to a 13-amino acid addition that pushes a vWF-binding domain further away from the platelet membrane surface.

  • Consequently, it remains uncertain whether one can extrapolate the MIRACL trial results to those who undergo coronary revascularization shortly before or after a coronary event, who present with a Q-wave myocardial infarction, who are treated with platelet glycoprotein IIb/IIIa inhibitors, or who have relatively low admission LDL cholesterol levels.

  • These candidate genes will make it possible to study not only polymorphisms associated with a hypercoagulable state, but also to study the genes involved in pathways that may lead to the development of vasculopathy (genes involved in endothelial cell function, inflammation, and adhesion, platelet activation and responsiveness).

  • In the second study, Tomer and coworkers [ 31 ] also demonstrated changes in platelet and red cell activation markers in subjects with SCD following fish oil supplementation for one year, resulting in fewer pain episodes compared to subjects supplemented with n-6 fatty acids.

  • Studies in South America detail the pain and oedema at the bite site and manifestations of autonomic nervous system stimulation (vomiting, diarrhoea, sweating, hypersalivation, bradycardia) that may be attributed to serine protease in Lachesis muta venom which causes hypotension by releasing kinins from plasma kininogen [ 8 ] . There are also cases of bleeding distant from the bite site such as gingival haemorrhage, epistaxis, haemoptysis, haematuria, uterine bleeding, soft tissue haematomas and very infrequently intrathoracic or intrabdominal bleeding [ 35 ] . Complications in the bitten limb can include secondary infections by Gram-negative organisms and acute renal failure among others [ 8 ] . There is a bothrojacarin-like 27 kDa protein in Bothrops species venom [ 36 ] . Bothrojacarin forms a non-covalent complex with thrombin, blocking its ability to induce platelet aggregation and fibrinogen clotting [ 8 36 ] . Haemostatic effects in Lachesis muta venom are attributable to an alpha-fibrin(ogen)ase and haemorrhagic metalloproteinases (LHF-1 and LHF-II) which have alpha-fibrin(ogen)ase activity [ 8 ] .


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