Example sentences for: plasmin

How can you use “plasmin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • One of great importance, urokinase (uPA) and its high affinity receptor, the GPI-anchored membrane CD87 (uPAR), is critical in tumour progression and its level of expression is correlated with poor prognosis of various cancers such as prostate [ 2 ] , breast [ 3 ] , colon [ 4 ] , ovarian [ 5 ] , gastric [ 6 ] , brain [ 7 ] , and lung cancer [ 8 ] . Urokinase (uPA) and its main product plasmin belong to the very early proteases [ 9 10 11 ] that activate the metallo-protease (MMP) cascade and therefore control cell motility, tissue remodelling and the activation of various angiogenic factors (VEGF, TGFβ).

  • MMP-9 is secreted in an inactive zymogen form and can be activated in vitro by the plasmin cascade and through other MMPs [ 30, 31, 32, 33].

  • Thrombin, or plasmin activity without PAI-1 was taken as 100%.

  • More importantly, Glu351 of PAI-1 is a specificity determinant for uPA, thrombin and plasmin, but not for tPA.

  • [ 15 27 ] The specificity of the two mutants toward thrombin and plasmin implicates that Glu351 of PAI-1 is involved in its specificity toward thrombin and plasmin.


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