Words similar to plaque-forming
Example sentences for: plaque-forming
How can you use “plaque-forming” in a sentence? Here are some example sentences to help you improve your vocabulary:
The natural phenomenon of spontaneous mutation, which occurs in the absence of drug selection, results in the accumulation of approximately six to eight TK-deficient variants per 10 4plaque-forming viruses in virus populations that have never been exposed to selective pressure [ 6 10 12 ] . Furthermore, HSV-2 clinical isolates were shown to have a higher frequency of spontaneous mutations resistant to ACV and PCV, approximately 30-fold, compared to HSV-1 isolates, and the majority of these mutations are in tk . Consistent with this observation, HSV-2 strains also exhibited approximately a 20- to 80-fold higher spontaneous mutation rate to cidofovir (HPMPC), an inhibitor of HSV Pol, resistance compared with HSV-1 [ 21 ] . Therefore, these naturally-occuring mutations are not unique to tk and TK substrates as detected with antiviral agents ACV and PCV, but were extended with the direct Pol inhibitor, HPMPC, to other loci, most likely pol .
This proposal is supported by recent evidence that either genetic modification of ADAM-10/α-secretase activity [67] or administration of bryostatin, a PKC activator [68], can modulate levels of brain Aβ in plaque-forming transgenic mice.
[6] questioned the role of cholesterol as the final common pathway in Aß load specification, since, in their experiments, low cholesterol per se apparently had no impact on brain Aß load in plaque-forming transgenic mice.
Each virus had a titer of about 10 8plaque-forming units per ml.
α-Secretase activation may explain how statins lower the risk for Alzheimer disease [69], since atorvastatin diminishes Aβ burden in plaque-forming transgenic mice [13].
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