Words similar to plaque-forming
Example sentences for: plaque-forming
How can you use “plaque-forming” in a sentence? Here are some example sentences to help you improve your vocabulary:
Viral populations are naturally heterogeneous; there are approximately 6 to 8 TK deficient variants per 10 4plaque-forming units (PFU) of HSV-1 (laboratory strains and clinical isolates) that have never been exposed to antiviral selection [ 6 13 15 17 ] . Resistance to nucleoside inhibitors of HSV arises readily in tissue culture probably by selection of pre-existing mutants [ 10 13 18 ] . Moreover, Field et al.
The natural phenomenon of spontaneous mutation, which occurs in the absence of drug selection, results in the accumulation of approximately six to eight TK-deficient variants per 10 4plaque-forming viruses in virus populations that have never been exposed to selective pressure [ 6 10 12 ] . Furthermore, HSV-2 clinical isolates were shown to have a higher frequency of spontaneous mutations resistant to ACV and PCV, approximately 30-fold, compared to HSV-1 isolates, and the majority of these mutations are in tk . Consistent with this observation, HSV-2 strains also exhibited approximately a 20- to 80-fold higher spontaneous mutation rate to cidofovir (HPMPC), an inhibitor of HSV Pol, resistance compared with HSV-1 [ 21 ] . Therefore, these naturally-occuring mutations are not unique to tk and TK substrates as detected with antiviral agents ACV and PCV, but were extended with the direct Pol inhibitor, HPMPC, to other loci, most likely pol .
Each virus had a titer of about 10 8plaque-forming units per ml.
[6] questioned the role of cholesterol as the final common pathway in Aß load specification, since, in their experiments, low cholesterol per se apparently had no impact on brain Aß load in plaque-forming transgenic mice.
Virus stocks were prepared by inoculating cells at 0.01 plaque-forming units per MRC-5 cell (PFU/cell).
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