Example sentences for: pi-

How can you use “pi-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Many PH domain proteins bind with high affinity to specific phosphoinositides such as PI-4,5-P2, PI-3,4-P2 or PI-3,4,5-P3 which are generated by PI-3 kinase [ 28 ] . This relationship was reflected by the high correlation coefficient (0.

  • Restoring PTEN protein or function to reduce PI-3Kinase signaling prevents tumor growth in animal models.

  • Rad3 is a member of the phosphoinositide 3-kinase related kinase (PIKK) family [ 31 ] . These proteins are large (> 200 kDa) and share a domain related to the catalytic domain of phosphoinositide 3-kinases (PI-3 kinases).

  • Adenoviral expression of wild-type PTEN can inhibit U87 tumor growth indicating that elevated PI-3Kinase signaling is responsible for the increased proliferation and survival of these cells [ 47 54 ] . Our subsequent studies were designed to test whether interruption of an upstream growth factor signal would have the same growth inhibitory effect as reintroduction of PTEN.

  • Direct inhibition of PI-3Kinase activity may not be feasible either as it is likely to have severe side effects.


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