Example sentences for: phosphotyrosine

How can you use “phosphotyrosine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As in the total cellular phosphotyrosine analysis, the levels of phosphotyrosine on PLCγ2 were indistinguishable between control and experimental cell lines.

  • By contrast, wild-type and mutant EGFRs containing the T790M mutation did not display a significant change in either phosphotyrosine induction or p-EGFR:t-EGFR ratios (Figure 4A and 4B).

  • However, even when more protein was present in the immunoprecipitate, little if any phosphotyrosine was detected in unstimulated cells (lanes 13 and 15).

  • Meiotically induced, Spo11 (Rec12)-dependent double-strand DNA (dsDNA) breaks have been demonstrated in budding yeast and fission yeast [ 12 13 14 15 ] . Spo11 almost certainly catalyzes these breaks, as it shares high homology with the A subunit of Topoisomerase VI of Sulfolobus shibatae [ 16 17 ] and it becomes linked by a phosphotyrosine linkage to the 5' end of the cleaved DNA [ 18 19 20 21 ] . Spo11 homologs have been identified in a wide range of eukaryotes, and available evidence suggests that initiation of meiotic recombination via Spo11-dependent dsDNA break formation is conserved [ 22 23 24 25 ] . Our results with the fission yeast S. pombe fully support this view (see results and discussion).

  • Interestingly, Tat, through the RGD motif, which controls integrin-based cell signaling, has been reported to mediate the activity of phosphotyrosine phosphatase(s).


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