Example sentences for: phosphotyrosine

How can you use “phosphotyrosine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Meiotically induced, Spo11 (Rec12)-dependent double-strand DNA (dsDNA) breaks have been demonstrated in budding yeast and fission yeast [ 12 13 14 15 ] . Spo11 almost certainly catalyzes these breaks, as it shares high homology with the A subunit of Topoisomerase VI of Sulfolobus shibatae [ 16 17 ] and it becomes linked by a phosphotyrosine linkage to the 5' end of the cleaved DNA [ 18 19 20 21 ] . Spo11 homologs have been identified in a wide range of eukaryotes, and available evidence suggests that initiation of meiotic recombination via Spo11-dependent dsDNA break formation is conserved [ 22 23 24 25 ] . Our results with the fission yeast S. pombe fully support this view (see results and discussion).

  • In addition, phosphotyrosine residues in Syk would provide additional sites for protein-protein interactions.

  • As in the total cellular phosphotyrosine analysis, the levels of phosphotyrosine on PLCγ2 were indistinguishable between control and experimental cell lines.

  • It is hypothesized that trans-tyrosine phosphorylation of the EGFR creates protein phosphotyrosine binding sites that act as a surrogate scaffold for ERK activation [ 7 ] . Since ORs share many similarities with LPAR and β 2 -ARs in the way they activate the ERK pathway [ 9 15 ] , we chose to examine whether RTK transactivation occurs and is a necessary aspect of δ-opioid-mediated ERK activation.

  • Expression of the Cas(SD) or the Src KM/Cas(SD), fusion did not result in any increase in total phosphotyrosine containing proteins nor in the tyrosine phosphorylation of the Cas SD (data not shown and see Fig.


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