Words similar to phosphotyrosine
Example sentences for: phosphotyrosine
How can you use “phosphotyrosine” in a sentence? Here are some example sentences to help you improve your vocabulary:
By contrast, wild-type and mutant EGFRs containing the T790M mutation did not display a significant change in either phosphotyrosine induction or p-EGFR:t-EGFR ratios (Figure 4A and 4B).
Thus c-crk interacts constitutively with downstream effectors such as C3G via its SH3 domains, and interacts in a phosphotyrosine dependent fashion with tyrosine phosphorylated receptors using its SH2 domain [ 39 ] . To analyze downstream signals regulated by these adaptor proteins, investigators have developed methods that target them to distinct cellular membrane compartments by using heterologous targeting sequences.
To determine if the constitutive Syk activity observed in unstimulated cells carrying the (K395A/3F) transgene was accompanied by constitutive Syk tyrosine phosphorylation, the levels of phosphotyrosine on Syk were determined by immunoblotting after immunoprecipitation (Figure 3F).
Further analysis demonstrated neither increases in phosphotyrosine nor phosphorylation of PLCγ2.
Meiotically induced, Spo11 (Rec12)-dependent double-strand DNA (dsDNA) breaks have been demonstrated in budding yeast and fission yeast [ 12 13 14 15 ] . Spo11 almost certainly catalyzes these breaks, as it shares high homology with the A subunit of Topoisomerase VI of Sulfolobus shibatae [ 16 17 ] and it becomes linked by a phosphotyrosine linkage to the 5' end of the cleaved DNA [ 18 19 20 21 ] . Spo11 homologs have been identified in a wide range of eukaryotes, and available evidence suggests that initiation of meiotic recombination via Spo11-dependent dsDNA break formation is conserved [ 22 23 24 25 ] . Our results with the fission yeast S. pombe fully support this view (see results and discussion).
Loading...