Words similar to phosphotyrosine
Example sentences for: phosphotyrosine
How can you use “phosphotyrosine” in a sentence? Here are some example sentences to help you improve your vocabulary:
Meiotically induced, Spo11 (Rec12)-dependent double-strand DNA (dsDNA) breaks have been demonstrated in budding yeast and fission yeast [ 12 13 14 15 ] . Spo11 almost certainly catalyzes these breaks, as it shares high homology with the A subunit of Topoisomerase VI of Sulfolobus shibatae [ 16 17 ] and it becomes linked by a phosphotyrosine linkage to the 5' end of the cleaved DNA [ 18 19 20 21 ] . Spo11 homologs have been identified in a wide range of eukaryotes, and available evidence suggests that initiation of meiotic recombination via Spo11-dependent dsDNA break formation is conserved [ 22 23 24 25 ] . Our results with the fission yeast S. pombe fully support this view (see results and discussion).
Expression of the Cas(SD) or the Src KM/Cas(SD), fusion did not result in any increase in total phosphotyrosine containing proteins nor in the tyrosine phosphorylation of the Cas SD (data not shown and see Fig.
IgM - immunoglobulin of the M isotype; ova - chicken ovalbumin; PY - phosphotyrosine; PLCγ2 - phospholipase C γ2; anti - antibody or antiserum generated against indicated antigen; RT-PCR - reverse transcriptase polymerase chain reaction; ICKA - immune-complex kinase assay; ITAM - immunoreceptor tyrosine-based activation motifs; SH2 and SH3 - Src homology domains 2 and 3; PBS - phosphate-buffered saline.
As in the total cellular phosphotyrosine analysis, the levels of phosphotyrosine on PLCγ2 were indistinguishable between control and experimental cell lines.
The second class of phosphotyrosine dependent adaptors exemplified by proteins such as Cas, Dok, IRS-1 and 2 or Slp-76, as cytosolic adaptors, or LAT, TRIM or SIT as membrane anchored adaptors, also require the activation of upstream signals by tyrosine kinases for their function.
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