Example sentences for: phosphoprotein

How can you use “phosphoprotein” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The BRCA1 gene encodes a 220-kDa nuclear phosphoprotein that is regulated in response to DNA damaging agents [ 5, 6, 7] and in response to estrogen-induced growth [ 8, 9, 10, 11].

  • Preparation of phosphoprotein substrates

  • RSV is a member of the Pneumovirus genus in the Paramyxoviridae family, and contains a nonsegmented negative-stranded RNA genome of about 15 kb [ 5 ] . The minimal viral RNA-dependent RNA polymerase (RdRP) consists of two virally encoded proteins, the large protein L and the phosphoprotein P [ 6 7 8 ] , and a third viral protein, M2-1 (22K), contributes RNA antitermination function and optimal processivity [ 9 ] . In addition to these viral proteins, the RdRP also requires cellular actin.

  • We have also shown that recombinant NFATp purified from insect cells is a phosphoprotein that exhibits association with nuclei in vitro only after dephosphorylation by calcineurin.

  • On the basis of sequence homo logy and similarity of three-dimensional structures, phosphoprotein phosphatases (PPases) have been classified into three families designated PPP, PPM, and PTP [reviewed in [ 1 2 3 ] . The PPP and PPM families are comprised of phosphoserine- and phosphothreonine-specific enzymes whereas the PTP family consists of phosphotyrosine-specific and dual-specificity enzymes [ 4 ] . The major members of the PPP family are PP1, PP2A, and PP2B (calcineurin) class of phosphatases.


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