Example sentences for: pharmacophore

How can you use “pharmacophore” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Hibert et al proposed an early model for the antagonist pharmacophore of the 5-HT 3 R [ 18 ] . According to this model, all 5-HT 3 R antagonists contain an aromatic ring, a carbonyl oxygen or bioisosteric equivalent, and a basic nitrogen.

  • While structure-activity relationship studies and molecular modeling have led to the development of a detailed pharmacophore model, determining specific point interactions between 5-HT 3 antagonists and binding site amino acids has proven difficult.


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