Words similar to pharmacophore
Example sentences for: pharmacophore
How can you use “pharmacophore” in a sentence? Here are some example sentences to help you improve your vocabulary:
Hibert et al proposed an early model for the antagonist pharmacophore of the 5-HT 3 R [ 18 ] . According to this model, all 5-HT 3 R antagonists contain an aromatic ring, a carbonyl oxygen or bioisosteric equivalent, and a basic nitrogen.
While structure-activity relationship studies and molecular modeling have led to the development of a detailed pharmacophore model, determining specific point interactions between 5-HT 3 antagonists and binding site amino acids has proven difficult.