Words similar to pharmacokinetics
Example sentences for: pharmacokinetics
How can you use “pharmacokinetics” in a sentence? Here are some example sentences to help you improve your vocabulary:
The "standard human" PBPK organ weights and blood flows are listed in Table I. These are the same values that have been used previously to model the pharmacokinetics of D 2 O and ethanol [ 24 ] , toluene and the volatile anesthetics [ 25 ] , propranolol [ 26 ] and inulin and protein bound antibiotics [ 27 ] . Two different PBPK models are used.
Two recent studies in models of Parkinson's disease and peripheral nerve damage support this claim, by demonstrating that pathway activation with a Hh-protein ligand has therapeutic value [ 49 50 ] . On the basis of our current understanding of these models and the specific mechanism of action of the Hh agonists, we predict that an agonist-derivative with low toxicity and favorable pharmacokinetics would replicate these positive results.
A recent review has described the confusion that has resulted from applying this definition to human ethanol pharmacokinetics, a compound that has extremely non-linear liver metabolism [ 1 ] .
It can be seen that the agreement is quite good and the differences in the pharmacokinetics for the two subjects can be explained by differences in the fat fraction.
The use of a PBPK to model pharmacokinetics requires detailed information about the blood-tissue partition coefficient for each organ.
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