Example sentences for: pharmacokinetics

How can you use “pharmacokinetics” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The "standard human" PBPK organ weights and blood flows are listed in Table I. These are the same values that have been used previously to model the pharmacokinetics of D 2 O and ethanol [ 24 ] , toluene and the volatile anesthetics [ 25 ] , propranolol [ 26 ] and inulin and protein bound antibiotics [ 27 ] . Two different PBPK models are used.

  • Two recent studies in models of Parkinson's disease and peripheral nerve damage support this claim, by demonstrating that pathway activation with a Hh-protein ligand has therapeutic value [ 49 50 ] . On the basis of our current understanding of these models and the specific mechanism of action of the Hh agonists, we predict that an agonist-derivative with low toxicity and favorable pharmacokinetics would replicate these positive results.

  • A recent review has described the confusion that has resulted from applying this definition to human ethanol pharmacokinetics, a compound that has extremely non-linear liver metabolism [ 1 ] .

  • It can be seen that the agreement is quite good and the differences in the pharmacokinetics for the two subjects can be explained by differences in the fat fraction.

  • The use of a PBPK to model pharmacokinetics requires detailed information about the blood-tissue partition coefficient for each organ.


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