Example sentences for: pericentric

How can you use “pericentric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The association of two independent chromosomal rearrangement events at one site: a pericentric inversion in the chimpanzee genome, and the insertion of a novel segmental duplication within the human lineage, may be a consequence of the overall genomic instability of this region.

  • It is currently unclear why the cell has two mechanisms to dissociate cohesin from chromosomes, although it is interesting to speculate that this could be related to different functions of cohesin at chromosome arms versus pericentric domains.

  • Using a panel of FISH probes spanning several known sites of rearrangement within 15q11-q13 we were able to narrow the region containing the PTR pericentric inversion breakpoint to a complex cluster of segmental duplications approximately 600 kb in length, according to the most recent assembly of the human genome.

  • During this analysis, chimpanzee, pygmy chimpanzee, gorilla and orangutan chromosomes were assayed for the species-specificity of the pericentric inversion (Figure 2).

  • Scc1/Mcd1 at pericentric regions is protected from phosphorylation during prophase—and therefore dissociation from chromosomes is prevented—by proteins known as shugoshins [35,36,37].


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