Words similar to pericentric

Example sentences for: pericentric

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Using a panel of FISH probes spanning several known sites of rearrangement within 15q11-q13 we were able to narrow the region containing the PTR pericentric inversion breakpoint to a complex cluster of segmental duplications approximately 600 kb in length, according to the most recent assembly of the human genome.
This reinforces the view that there may be functional differences in arm and pericentric cohesion and perhaps different mechanisms to load cohesin, as has been proposed for cohesin on meiotic chromosomes for
Recent studies have characterized several evolutionary breakpoints in common chimpanzee and other great ape species including pericentric inversions and a chromosome translocation [ 7 8 9 ] . We present here a refinement of the breakpoint associated with a previously identified pericentric inversion of the human 15q11-q13 orthologous region in common chimpanzee (XVp) to a region containing multiple segmental duplications [ 1 2 10 ] .
These results imply that either the pericentric inversion involved the duplication of a large chromosomal segment, or that the inversion involved a sequence common to all clones in the 600 kb interval.
Scc1/Mcd1 at pericentric regions is protected from phosphorylation during prophase—and therefore dissociation from chromosomes is prevented—by proteins known as shugoshins [35,36,37].