Example sentences for: periarticular

How can you use “periarticular” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The ability of Ad-mIL-4 to treat established CIA was evaluated by local periarticular and systemic intravenous injection of Ad-mIL-4 into mice at various times after disease onset.

  • Although the pathologic processes that underlie the development of erosions are incompletely understood, a considerable body of evidence has suggested that a pannus of cells that originate in chronically inflamed, proliferative synovial tissue becomes locally invasive, and enzymatically degrades the matrix of the articular cartilage and periarticular bone [ 4].

  • To examine the therapeutic effects of IL-4 gene transfer in a murine model of arthritis, 5×10 8particles of Ad-mIL-4 and enhanced green fluorescent protein (Ad-eGFP) were administered by periarticular injection into the ankle joints of mice with established disease 4 days after lipopolysaccharide injection.

  • We have demonstrated previously that periarticular injection of adenovirus-mediated gene transfer of v-IL-10 into the hind paws of mice with early-stage arthritis was able to confer a therapeutic effect in the untreated front paws.

  • In the present study we examined the ability of local periarticular gene transfer of IL-4 to treat established murine CIA.


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