Words similar to peri-implantation
Example sentences for: peri-implantation
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Prenatal mortality in the pig ranges from 20% to 46% by term [ 1 ] , the majority of which occurs during peri-implantation conceptus development [ 2 ] . The peri-implantation period is the most critical stage of conceptus development as a rapid morphological transformation of the trophoblast occurs just prior to conceptus attachment to the uterine surface [ 3 ] . Rapid transformation of the trophoblast, termed trophoblastic elongation, occurs during days 11 to 12 of gestation.
This is in agreement with previous studies which demonstrate that EP 2 is expressed and highly regulated in uterine luminal epithelium cells by ovarian steroids during the peri-implantation period [ 5 21 34 35 ] . The change in level of the EP 2 receptor expression in the uterus may contribute to the increase in G S protein content and cAMP concentration in mid-gestation and the decrease at term [ 26 27 ] . Because the EP 2 receptor is a G S -coupled cAMP-stimulating receptor, the EP 2 receptor may participate in the physiological regulation of uterine relaxation during pregnancy and the transition into uterine contraction at the onset of the labor.
[ 10 ] evaluated peri-implantation gene expression profiles for 17α-hydroxylase, aromatase, brachyury and leukemia inhibitory factor receptor, all of which are more greatly expressed in filamentous conceptuses.
During early porcine development a rapid morphological transformation of the conceptus from a spherical (9-10 mm) to filamentous (> 150 mm) morphology is required to establish adequate placenta to uterine contact necessary for survival [ 2 ] . Characterization of the specific subset of genes regulating peri-implantation conceptus development and trophoblastic elongation in the pig provides valuable information concerning key developmental events essential to embryonic survival after trophoblastic elongation [ 1 ] .
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