Example sentences for: peri-centromeric

How can you use “peri-centromeric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We observed that C/EBPα, expressed in mouse pituitary progenitor GHFT1-5 cells, also localized to peri-centromeric chromatin [ 45 ] . Here we show that targeting of C/EBPα to peri-centromeric chromatin in GHFT1-5 cells required the DNA binding domain of C/EBPα (Fig.

  • The independence of C/EBPα regulation of proliferation from its intranuclear localization may even be necessary since we have recently determined that pituitary cell differentiation is associated with the dispersal of C/EBPα from peri-centromeric heterochromatin by the pituitary-specific transcription factor Pit-1 (J.

  • Thus, leucine zipper dimerization, site-specific DNA binding and targeting of C/EBPα to peri-centromeric were not required for C/EBPα prolongation in G1 and S. In contrast, the isolated C/EBPα bZIP DNA binding domain (Fig.

  • 2C) by eliminating the leucine zipper required for DNA binding by all members of the bZIP family of transcription factors [ 52 ] . Thus, as predicted [ 49 ] , the bZIP domain is necessary and sufficient for C/EBPα targeting to peri-centromeric chromatin.

  • 1B, DBD), which still targeted to peri-centromeric chromatin, did not prolong G1 (Fig.


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