Words similar to peri-centromeric
Example sentences for: peri-centromeric
How can you use “peri-centromeric” in a sentence? Here are some example sentences to help you improve your vocabulary:
The independence of C/EBPα regulation of proliferation from its intranuclear localization may even be necessary since we have recently determined that pituitary cell differentiation is associated with the dispersal of C/EBPα from peri-centromeric heterochromatin by the pituitary-specific transcription factor Pit-1 (J.
2C) by eliminating the leucine zipper required for DNA binding by all members of the bZIP family of transcription factors [ 52 ] . Thus, as predicted [ 49 ] , the bZIP domain is necessary and sufficient for C/EBPα targeting to peri-centromeric chromatin.
Thus, the specific association of C/EBPα with peri-centromeric chromatin, speculated to contribute to C/EBPα growth arrest [ 49 ] , was not necessary for disruption of the cell cycle by C/EBPα.
1B, DBD), which still targeted to peri-centromeric chromatin, did not prolong G1 (Fig.
Thus, leucine zipper dimerization, site-specific DNA binding and targeting of C/EBPα to peri-centromeric were not required for C/EBPα prolongation in G1 and S. In contrast, the isolated C/EBPα bZIP DNA binding domain (Fig.