Example sentences for: pedf-receptor

How can you use “pedf-receptor” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The fact that the binding of PEDF to cell surfaces decreases with heparin/HS depletion, implies that heparin/HS molecules might act as cofactors for PEDF-receptor interactions.

  • We investigated the effect of components of the CM, a source of extracellular matrix, on the PEDF-receptor interactions using CM and non-conditioned defined media in radioligand binding assays.

  • These observations showed that a component(s) secreted by retinoblastoma cells enhanced the PEDF-receptor interactions.

  • GAG-binding proteins can be differentially sensitive to variations in GAG structure [ 27 ] . GAGs produced among different cell types have structural and compositional differences and structural changes in GAGs are known to occur in cells undergoing morphological differentiation and/or malignant transformations [ 28 29 30 31 ] . Thus, in the native retina, or other tissue, modulation of the PEDF-receptor interactions may depend on the expression of GAGs, which occur during development and pathological conditions.

  • Note that with the binding method used, the amount of 125I-PEDF retained in CM without cells is the same to the amount of non-specific 125I-PEDF binding (reactions with cells and in the presence of 50-fold molar excess of unlabeled PEDF) [ 18 ] , indicating retention by PEI-treated glass-fiber filters of PEDF-receptor or GAG-PEDF-receptor complexes rather than PEDF-GAG.


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