Example sentences for: pedf

How can you use “pedf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The primary consequence of reducing the heparin/HS and its sulfation was to minimize a binding site required for PEDF activity.

  • These possibilities are discussed under the consideration that some of them may have important implications if PEDF, or molecules derived from it, are to be used in the future as therapeutic agents.

  • In this assay, soluble PEDF of 50-kDa is filtered through a membrane with an exclusion limit of MW 100,000, however it is retained upon formation of a complex larger than this limit [ 14 ] . The binding reactions were with a given 125I-PEDF concentration and CM.

  • It has been proposed that the GAG-binding property of PEDF provides the molecular basis for its association with extracellular matrices and may serve to localize PEDF activity in the retina and CNS [ 14 19 ] . However, the present results point to direct effects these polysaccharides might have on the biochemical interactions between PEDF and PEDF receptors on the surfaces of cells that respond to this neurotrophic factor.

  • The final fraction (CM PEDF) contained components with binding affinity for PEDF that stained with Toluidine Blue-O and migrated as high molecular weight GAGs.


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