Words similar to pedf

Example sentences for: pedf

How can you use “pedf” in a sentence? Here are some example sentences to help you improve your vocabulary:

Complex formation between PEDF and CM components was assayed by a method using ultrafiltration through membranes of 100,000 MW exclusion limit [ 14 ] . Binding reactions were performed with a given concentration of 125I-PEDF in defined or conditioned media, and incubations with gentle rotation at 4°C for 2 h.
It has been proposed that the GAG-binding property of PEDF provides the molecular basis for its association with extracellular matrices and may serve to localize PEDF activity in the retina and CNS [ 14 19 ] . However, the present results point to direct effects these polysaccharides might have on the biochemical interactions between PEDF and PEDF receptors on the surfaces of cells that respond to this neurotrophic factor.
Cell-associated HS proteoglycans can undergo regulated shedding from the membrane into the soluble extracellular matrix or culturing medium converting the membrane anchored molecules into soluble effectors [ 1 2 ] . In the conditioned media of all the tested batches of retinoblastoma cells, we detected heparin and HS with binding affinity for PEDF.
These observations revealed that the retained forms in the CM were PEDF complexes ≥ 100-kDa, and that the majority of these complexes were formed with soluble CM components other than proteins.
Because PEDF coexists with GAGs in extracellular matrices and has binding affinity for them, it is of interest to investigate the role of GAGs on PEDF activity.