Words similar to pedf
Example sentences for: pedf
How can you use “pedf” in a sentence? Here are some example sentences to help you improve your vocabulary:
The binding of GAGs to PEDF that modulate the binding of these factors to its receptor opens also the possibility that different GAGs may modulate differently the affinity of PEDF for its receptors, by increasing or even decreasing it in some cases.
The fact that the binding of PEDF to cell surfaces decreases with heparin/HS depletion, implies that heparin/HS molecules might act as cofactors for PEDF-receptor interactions.
Given that binding to cell-surface receptors is the first step in the biological activity of PEDF, we used human retinoblastoma Y-79 cells and their conditioned media (CM) as sources of functional PEDF receptors and extracellular matrix components, respectively, to examine the GAG content in CM and their effects on PEDF ligand-receptor interactions.
In the PEDF spatial structure, the putative GAG binding domain is distinct from and non-overlapping with the neurotrophic active region [ 14 20 ] .
The data suggest that heparan sulfate participates in the formation of a PEDF binding complex with its cell-surface receptor, and constitutes a positive modulator for the PEDF-receptor interactions.
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