Example sentences for: pedf

How can you use “pedf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Because PEDF coexists with GAGs in extracellular matrices and has binding affinity for them, it is of interest to investigate the role of GAGs on PEDF activity.

  • Thus, these observations implied that HS/heparin might play a functional role in the binding of PEDF to its cell-surface receptor.

  • The data suggest that heparan sulfate participates in the formation of a PEDF binding complex with its cell-surface receptor, and constitutes a positive modulator for the PEDF-receptor interactions.

  • In a spatial structure of PEDF, the heparin/HS binding domain of PEDF maps to the opposite side of the neurotrophic active region [ 20 ] , allowing distinct and non-overlapping interactions with heparin/HS on one side of the protein, and with the neurotrophic receptor on its opposite side.

  • PEDF binding to cell-surface receptors was assayed using biologically active radioligand 125I-PEDF and Y-79 cells [ 18 ] by a widely-used method with a mechanism of retention of receptors on polyethylenimine-treated glass-fiber filters based mainly on ionic interactions [ 32 ] . Polyethylenimine binds strongly to glass, which is negatively charged and integral membrane proteins tend to be acidic.


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