Words similar to pdz

Example sentences for: pdz

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This motif helps in the binding of the MAGUK with the C-terminus of proteins that have the consensus E (S/T) × (V/l) motif [ 19 ] . However the studies on the Drosophila protein InaD, which also has a PDZ domain, show that are other targets for the PDZ domain that do not have the consensus C-terminus binding motif [ 20 ] . Thus in DLG5 the PDZ domain may be binding to other targets that do not require the classic GLGF motif for interaction.
These myosins have a unique amino-terminal PDZ domain.
The MAGUK family of proteins [ 2 10 ] have characteristic domains which are present in DLG5: PDZ1 at bp 3763-4074, PDZ 2 domain 4186-4518 bp, SH3 domain bp 4570-4782 and the GUK domain at bp 4915-5539 (Figure 2).
The number of examples in this category could be increased, and some have already been considered in the literature, for example the spurious discovery of a 'functional PDZ domain' in the molecular chaperone ClpA ([ 46], see refutation in [ 47]) or the finding of an ATPase domain and death effector domains in the apoptosis-associated protein FLASH ([ 48], see refutation in [ 49]).
The DLG5 gene encodes for 2 PDZ domains, with another region in the N-terminus having very weak homology to an additional two PDZ domains.