Words similar to parkinson
Example sentences for: parkinson
How can you use “parkinson” in a sentence? Here are some example sentences to help you improve your vocabulary:
A kind of Parkinson's Law may be in effect here: words will increase in number to occupy the pages publishers are willing to print.
I always felt sorry for Cecil Parkinson when he was Trade and Industry Secretary as “inDUStry”--the “DUS” rhyming with bus --was one of the few words that gave him away.
For example, strokes to the posterior parietal lobe involved in orienting produce neglect of the contralesional space and specific deficits in tasks involved the orienting network [ 12 ] . Reductions in striatal dopamine seen in Parkinson's disease result in an inability to shift sets from one instruction to another, possibly reflecting a difficulty in control of conflict [ 13 ] . Many psychiatric disorders whose anatomical origins may not be well understood also show deficits in attention.
Recent studies on neurodegenerative diseases, including Parkinson's, Alzheimer's and prion diseases, suggest that it is not the long fibrils that produce toxicity and kill neurons, rather, it is the oligomeric aggregation intermediates that produce toxicity [ 54 55 ] . Interestingly, interactions between biomembranes and toxic proteins produce a dual effect of both promoting oligomeric aggregation of the proteins and membrane damage [ 56 57 58 59 ] , suggesting that one possible toxicity of oligomeric aggregates is mediated through damaging membranes.
In recent years, it has become clear that the neuronal nAChR is a valid target against a variety of diseases, including cognitive and attention deficits, Parkinson's disease, anxiety, and pain management [ 3 4 ] ; the addiction liability and other undesirable side-effects of nicotine prohibit the use of this natural product for therapeutic applications, but the active development of nAChR agonists presenting adequate receptor subtype specificity should result in improved pharmacology and potency [ 4 ] . As for most membrane proteins, information on the 3 dimensional structure of the nAChR is limited, and the best experimental structure consists of 4.6 A data from electron microscopy [ 5 ] , a resolution that does not allow for structure-based design approaches.
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