Example sentences for: parkin

How can you use “parkin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Furthermore, parkin does not just prevent α-synuclein toxicity: it is beneficial against several other stresses (discussed in Shen and Cookson 2004), leading to the possibility that this protein protects neurons against more than just the processes implicated in PD.

  • We have shown that parkin can mitigate the toxicity of mutant α-synuclein (Petrucelli et al.

  • On balance, therefore, there is no direct evidence that parkin controls α-synuclein toxicity by an effect on protein levels within the cell.

  • Parkin is an E3 ubiquitin–protein ligase, promoting the addition of ubiquitin to target proteins prior to their degradation by the proteasome.

  • Therefore, our best evidence to date indicates that parkin benefits neurons by removing proteins that might otherwise damage the cell.


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