Example sentences for: parkin

How can you use “parkin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have shown that parkin can mitigate the toxicity of mutant α-synuclein (Petrucelli et al.

  • On balance, therefore, there is no direct evidence that parkin controls α-synuclein toxicity by an effect on protein levels within the cell.

  • The genes involved in recessive parkinsonism are, in order of discovery, parkin, DJ-1, and PINK1 . The three protein products of these genes all have different functions, thus implicating several different cellular functions in neuroprotection.

  • Although there are reports that a proportion of α-synuclein is a parkin substrate (Shimura et al.

  • Parkin is an E3 ubiquitin–protein ligase, promoting the addition of ubiquitin to target proteins prior to their degradation by the proteasome.


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