Example sentences for: paratuberculosis

How can you use “paratuberculosis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The results of this study provides further insight surrounding M. paratuberculosis -macrophage infections and have implications in the pathogenesis of M. paratuberculosis, a pathogen known to persist inside cattle for many years.

  • While these sequencing efforts have revealed a conserved gene order in the oriC of Gram-positive bacteria [ 11 ] , the nucleotide and amino acid identity between M. paratuberculosis and M. avium in this region is much stronger when compared to other mycobacteria and other Gram-positive bacteria (see Table 2).

  • M. paratuberculosis is an intracellular pathogen that infects ruminant animals, most notably cattle and sheep.

  • The site of infection is the gastrointestinal tract, where it causes a chronic inflammatory ailment termed Johne's disease [ 5 ] . In contrast, M. avium is common in the environment, causes tuberculosis in birds, and disseminated infections in HIV patients [ 6 ] . Growth of M. paratuberculosis is characterized by its slow rate (doubling time of 22-26 hours, compared to 10-12 hours for M. avium ) and requirement of mycobactin in culture media [ 5 ] . With the absence of a well-defined genetic system for M. paratuberculosis , a comparative genomic approach holds great potential in addressing the genetic basis for many of these phenotypic differences.

  • Second, we examined nucleotide identity outside the oriC region using DNA homology matrix analysis as well as using several hundred M. paratuberculosis sequences from a random shotgun library compared with M. avium sequences present in the unfinished microbial genomes database.


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