Words similar to parathyroid
Example sentences for: parathyroid
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Intestinal calcium absorption is increased after feeding a low calcium diet or under conditions of increased calcium needs, such as during growth, via a parathyroid hormone (PTH)-vitamin D mediated process [ 3 ] . A lowering of serum calcium levels stimulates the secretion of PTH that then activates the renal conversion of inactive 25-hydroxyvitamin D to the active hormonal metabolite 1,25-dihydroxyvitamin D. At the intestine, 1,25-dihydroxyvitamin D, acting through a nuclear receptor, stimulates transcription of vitamin D-mediated genes, including calbindin D, involved in calcium transport thereby acting as the primary hormonal regulator of active intestinal calcium transport [ 3 ] . It is thus likely that any putative key molecular player in calcium absorption, such as CaT1 or ECaC1, should be a prime target for hormonal regulation by 1,25-dihydroxyvitamin D. However, to date, neither CaT1 nor ECaC1 expression has been shown to be related to serum 1,25-dihydroxyvitamin D or vitamin D status [ 10 16 ] .
Familial hyperparathyroidism may be confined to parathyroid adenoma (HRPT1 #145000) or may involve the broader endocrine disturbances of multiple endocrine neoplasia Types I (#131100) and IIA (#171400).
Adherent cells were transduced with an amphotropic retrovirus, DFG-hIL-1β-neo, which encodes the mature form of human IL-1β fused to the leader sequence of human parathyroid hormone to enable efficient secretion, and neomycin phosphotransferase [ 21 ] . Retroviral transductants were positively selected in complete DMEM containing Geneticin at 0.5 mg/ml.
The only bone anabolic agent known to increase bone mineral density in both animal models and clinical settings is human parathyroid hormone 1-34 (PTH), which has recently been approved by the FDA in patients with advance osteoporosis [ 10 ] . Bone-related basic and clinical research has been searching intensively for alternative anabolic agents for the treatment of osteoporosis.
Parathyroid Hormone/Parathyroid hormone related peptide Receptor (PTH/PTHrP-R; L28108); forward primer: 5'-GAAAGAATAAAGCAAAAGCGAGACA-3'(232-256); reverse primer: 5'-AGGGAGCTCTGACATCGGG-3'(299-281).
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