Words similar to paramutation

Example sentences for: paramutation

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Paramutation has been studied extensively for four maize loci that encode transcriptional regulators of pigment biosynthesis [ 1 ] . Paramutation has also been investigated in the Arabidopsis PAI gene family, at the a1 and chalcone synthase (CHS) transgene loci in petunia, and in a number of other cases [ 2 3 4 ] . The Arabidopsis resistance gene BAL/CPR1 displays a related form of epigenetic instability [ 5 6 ] . Interactions resembling paramutation also occur among non-allelic transgene loci with DNA sequence homology.
If allelic, such non-Mendelian interactions are referred to as paramutation.
Epigenetic activity, defined here as partnership in heritable trans-silencing or paramutation, is not predictable from the DNA sequence alone, and its molecular basis is incompletely understood.
In these cases one master locus tends to suppress the expression of its target locus ('trans-silencing') [ 7 8 9 10 11 ] . Paramutation and trans-silencing are related processes.
Likewise, Arabidopsis PAI2 and PAI3 genes that have been trans-methylated by the PAI1/PAI4 locus do not transfer their methylation status to naive singlet genes [ 12 ] . In fact, there are few well-documented cases for the non-allelic relay of trans-silencing ability [ 11 24 ] . Does this amount to an operational difference between allelic (paramutation) and non-allelic (trans-silencing) interactions, or does it simply reflect a lack of data?