Words similar to paramutation

Example sentences for: paramutation

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These repeats are often part of the trans-silencer locus or paramutagenic locus or its target [ 10 14 15 16 17 ] . However, the repeat can sometimes be located at a considerable distance from the affected locus itself, as has recently been shown for the single-copy maize b1 gene [ 18 ] . Other than transcriptional gene silencing, paramutation is only weakly correlated with DNA methylation.
In the classical case of paramutation at the maize b1 locus, the imprint is relayed with 100% efficiency [ 24 ] . That is, a paramutated allele is turned into a paramutagenic allele.
These data suggest that the competence for trans-silencing may be transferred between non-allelic transgenes, reminiscent of the allelic transfer of epigenetic activity during paramutation.
Epigenetic activity, defined here as partnership in heritable trans-silencing or paramutation, is not predictable from the DNA sequence alone, and its molecular basis is incompletely understood.
These results underscore the similarity between trans-silencing and paramutation, because in both cases epialleles are often silenced incompletely and may also adopt novel regulatory patterns [ 4 10 ] , for example light inducibility [ 33 ] . Perhaps, silencing at the dimeric E82 locus involves a hierarchical relationship between its two intact T-DNAs.