Words similar to paracrine
Example sentences for: paracrine
How can you use “paracrine” in a sentence? Here are some example sentences to help you improve your vocabulary:
As there is no evidence that primordial follicles express BMP ligands, the mechanism by which this activation occurs would be paracrine, most likely involving BMP-7 from adjacent tissues such as the theca, secondary interstitial, or sex cords.
The role of hormones in this process is clear; however, new results indicate that autocrine/paracrine or growth factor mechanisms also have important roles.
Both PGE 2 and a cascade of proteolytic events that lead to extracellular matrix degradation have the potential for serving as paracrine regulators.
Less obvious abnormalities in ciliary body tissues may also affect IOP by altering the volume or composition of the aqueous humor produced and possibly by altering the drainage structures in a paracrine fashion [ 42 ] . Thus, more subtle metabolic abnormalities in the ciliary body may interact with the iridocorneal angle phenotypic variation and contribute to variability in IOP elevation between human patients.
The concept of lung fibroblasts as effector cells in the pathogenesis of idiopathic pulmonary fibrosis (IPF) has recently evolved [ 1 2 ] . Lung fibroblasts respond, in vitro , to inflammatory cytokines by producing growth factors and collagen, resulting in fibroblast proliferation and extracellular matrix deposition [ 2 3 4 ] . In addition, activated lung fibroblasts have been shown to produce large amounts of inflammatory cytokines and chemokines, in vitro , and hence, these cells may also have a role as effector-inflammatory cells [ 1 2 ] . This capacity to produce both inflammatory and fibrotic factors could mean that phenotypically altered lung fibroblasts act simultaneously as effector and target cells, via paracrine and autocrine mechanisms, perpetuating the fibrotic process [ 2 ] .
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