Words similar to paracrine
Example sentences for: paracrine
How can you use “paracrine” in a sentence? Here are some example sentences to help you improve your vocabulary:
They may represent a unique paracrine mechanism, so called "targeted delivery," by which certain growth factor (vesicle content) is delivered by chemotaxis to certain type/stage specific target cells expressing receptor for Thy-1 ligand.
The concept of lung fibroblasts as effector cells in the pathogenesis of idiopathic pulmonary fibrosis (IPF) has recently evolved [ 1 2 ] . Lung fibroblasts respond, in vitro , to inflammatory cytokines by producing growth factors and collagen, resulting in fibroblast proliferation and extracellular matrix deposition [ 2 3 4 ] . In addition, activated lung fibroblasts have been shown to produce large amounts of inflammatory cytokines and chemokines, in vitro , and hence, these cells may also have a role as effector-inflammatory cells [ 1 2 ] . This capacity to produce both inflammatory and fibrotic factors could mean that phenotypically altered lung fibroblasts act simultaneously as effector and target cells, via paracrine and autocrine mechanisms, perpetuating the fibrotic process [ 2 ] .
Because the OSE does not appear to express BMP receptors, the OSE-derived BMP-4 probably acts as a paracrine growth factor in the underlying stroma.
Various cytokines are also produced by biliary epithelial cells [ 14 ] . As biliary epithelial cells are capable of both producing and responding to cytokines, these cells may use cytokines for the autocrine/paracrine regulation of their own function as well as that of other cells.
Because SC were occasionally found juxtaposed to developing follicles, blood vessels and secondary interstitial cells, one cannot exclude the possibility that the SC-derived BMPs may have paracrine functions.
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