Words similar to paracrine
Example sentences for: paracrine
How can you use “paracrine” in a sentence? Here are some example sentences to help you improve your vocabulary:
An association between autocrine IL-6 and PCA has been known for some time [ 16 17 ] . The change in prostate cell phenotype from paracrine IL-6-stimulated to autocrine IL-6-stimulated is believed to be a contributing factor in the progression from benign hyperplasia to neoplasia [ 17 ] . IL-6 is also implicated in the development of cancer cell resistance to chemotherapy in PCA patients [ 18 19 ] . In other studies, a chimeric protein consisting of an anti-IL-6 Ab fused to Pseudomonas exotoxin was found to inhibit proliferation of prostate carcinoma cell lines [ 20 ] . Exogenous IL-6 activated androgen responsive gene expression in the absence of androgens in human LNCaP cells [ 21 ] . More work is needed to clarify the role of IL-6 in prostate neoplasia.
Because SC were occasionally found juxtaposed to developing follicles, blood vessels and secondary interstitial cells, one cannot exclude the possibility that the SC-derived BMPs may have paracrine functions.
Various cytokines are also produced by biliary epithelial cells [ 14 ] . As biliary epithelial cells are capable of both producing and responding to cytokines, these cells may use cytokines for the autocrine/paracrine regulation of their own function as well as that of other cells.
, which is responsive to polycyclic ligands present in environmental toxicants) in promoting apoptosis during fetal oogenesis has recently been identified in mice [ 43 44 ] . Prospective endocrine/paracrine modifiers (which are altered by nutritional regimen) of the fates of fetal germ cells include glucocorticoids, thyroid hormones, insulin, growth hormone, insulin-like growth factors, and leptin [ 1 45 ] .
OPG is currently hypothesized to be an important paracrine mediator of the antiresorptive action of estrogen on bone cells [ 25].
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