Example sentences for: papain-like

How can you use “papain-like” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The NlpC/P60 domain is predicted to adopt a papain-like fold, in which the catalytic cysteine is at the amino terminus of a helix, which is packed against a five-stranded β-barrel with the histidine and the polar residue.

  • In the case of papain-like proteases - calpains, transglutaminases and NH 2 -acetyltransferases - the three-stranded sheet of the core is incorporated into β-barrel with five to eight constituent strands (Figure 2).

  • Such substitutions have previously been observed in other papain-like peptidases with the serine participating in a functional active site [ 61, 62].

  • This difference may also explain the failure of sequence-structure threading algorithms, such as the combined fold prediction and 3DPSSM [ 39], to recover any significant hits to the papain-like proteases.

  • However, in the NlpC/P60 domain, the distance between the helix bearing the catalytic cysteine and the core barrel is similar to that seen in the transglutaminases and NH 2 -aminotransferases, suggesting that it lacks the large insert that is seen in several papain-like proteases (Figure 2).


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