Words similar to papain-like

Example sentences for: papain-like

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In the case of papain-like proteases - calpains, transglutaminases and NH 2 -acetyltransferases - the three-stranded sheet of the core is incorporated into β-barrel with five to eight constituent strands (Figure 2).
This suggests that despite the absence of significant sequence similarity, the NlpC/P60 domain is likely to contain a structural core corresponding to the classical papain-like protease fold (Figure 2).
The NlpC/P60 domain is predicted to adopt a papain-like fold, in which the catalytic cysteine is at the amino terminus of a helix, which is packed against a five-stranded β-barrel with the histidine and the polar residue.
A comparison of the predicted secondary structure for this superfamily with known peptidase folds revealed that these three residues show exactly the same arrangement as the catalytic triad of papain-like thiol peptidases.
This difference may also explain the failure of sequence-structure threading algorithms, such as the combined fold prediction and 3DPSSM [ 39], to recover any significant hits to the papain-like proteases.