Example sentences for: pancreatic

How can you use “pancreatic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, a recently published report on this association, based on a prospective cohort of 28,283 post-menopausal women, described a trend of decreasing risk of pancreatic cancer with increased weekly aspirin use [ 30 ] .

  • Because of the large number of patients seen at the Roswell Park Cancer Institute over the long study period (1982-1998), close to 200 pancreatic cancer patients were included in the analysis.

  • The pancreatic islets were evaluated blindly with semi-quantitative morphological scoring of fluorescent intensity: 0, no or very weak Ogg1 staining; 1, moderate Ogg1 staining; and 2, strong Ogg1 staining.

  • As packyears of cigarettes smoked smoking (packs per day × years of smoking) and family history of pancreatic cancer were found to be predictors of disease in our data, they were adjusted for in the regression models, along with age.

  • One of the hallmarks of cancer includes the accumulation of mutations in key genes, namely DNA repair genes [ 4 ] , tumor suppressor genes [ 5 6 ] , and proto-oncogenes [ 5 6 ] , accompanied by the loss of the wildtype allele, resulting in loss of heterozygosity [LOH, see reviews by [ 7 8 9 ] ]. Pancreatic cancer, which results in the death of approximately 30,000 Americans annually and is the fourth leading cause of cancer mortalities in the United States, exhibits this hallmark [ 10 ] . For example, in pancreatic cancer there is a high incidence of mutations (>50%) in the tumor suppressor genes p16, p53 and DPC4 and approximately 90% of cases coincide with a mutation in the oncogene K- ras 2 [see review by [ 11 ] ]. Furthermore, a significant percentage of tumors harboring a mutated copy of DPC4 or p53 also lose the corresponding wildtype allele, resulting in LOH [see reviews by [ 11 12 ] ].


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