Words similar to pancreatic
Example sentences for: pancreatic
How can you use “pancreatic” in a sentence? Here are some example sentences to help you improve your vocabulary:
In general, the risk estimates and 95% confidence intervals obtained following adjustment for smoking and family history of pancreatic cancer were very similar to the unadjusted, crude results.
These findings are consistent with the observation that 12-O-tetradecanoylphorbol 13-acetate lowers [Ca 2+] i at a stimulatory glucose concentration in pancreatic islets from obese-hyperglycaemic mice [ 16 ] . Since PMA increased K ATP activity (Fig.
The first, the ER overload response, triggers the activation of the transcription factor NFkB and the subsequent upregulation of inflammatory proteins [ 13 ] . The second, the unfolded protein response (UPR) induces three divergent cellular events: (i) the activation of transcription factor ATF6 leading to the upregulation of ER chaperones such as protein disulfide isomerase, (ii) upregulation of the pro-apoptotic transcription factor GADD153 and (iii) suppression of protein synthesis via phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) by pancreatic eIF2α kinase (PEK/PERK, [ 11 12 ] ). Upregulation of the ER chaperones, GADD153 and PERK in response to a toxic insult would constitute direct evidence of an ER stress response.
BPTI: Bovine Pancreatic Trypsine Inhibitor
Phorbol esters are often used as activators of protein kinase C (PKC) to investigate the role of the kinase in cellular functions [ 1 ] . Pancreatic β-cells possess α, β1, δ and ε PKC isotypes [ 2 ] , and activation of PKC is known to synergize with glucose stimulation in insulin secretion [ 3 4 5 ] . PKC, via protein phosphorylation seems to facilitate exocytosis of insulin granules [ 6 7 8 ] . In glucose-stimulated insulin secretion, ATP-sensitive K +channels (K ATP (SUR1, Kir6.
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