Example sentences for: pam

How can you use “pam” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The distance matrix was obtained using Protdist with a Dayhoff Pam matrix.

  • The clustering procedure PAM was used in the comparison; however, one should keep in mind that different clustering procedures can generate different partitions of the same data, possibly leading to different inferences about the number of clusters.

  • Pairwise evolutionary distances between the sequences in concatenated alignments were calculated using the Dayhoff PAM model as implemented in the PROTDIST program of the PHYLIP package [ 44 ] . A distance tree was constructed from the resulting distance matrix by using the least-square [ 46 ] method as implemented in the FITCH program of PHYLIP [ 44 ] . The maximum likelihood tree was constructed with the JTT-F model of amino acid substitutions [ 47 ] , as implemented in the ProtML program of the MOLPHY package [ 48 ] , by optimizing the least squares tree with local rearrangements.

  • When the PAM procedure is applied to the NCI60 dataset using the 200 genes with the largest variance and varying the number of clusters K ≤ 8, only five types of cell lines tend to cluster together (CNS, colon, leukemia, melanoma, and renal cell lines).

  • When the PAM procedure is applied to the leukemia dataset using the 100 genes with the largest variance, the results are as follows.


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