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Example sentences for: pairings
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Comparative genomic analyses of orthologous drosophilid genes should aid in this endeavor, as evidenced by the recent demonstration that several conserved motifs in the 3' UTR of the pro-apoptotic gene hid are targets of the miRNA bantam [ 44 ] . Statistically significant pairings of conserved and/or overrepresented 3' UTR motifs can be assessed for complementarity to miRNAs.
Experimental evidence suggests a functional role for sense-antisense pairings at a surprising variety of levels in mammalian gene regulation, including genomic imprinting [ 4, 5], RNA interference [ 6], translational regulation [ 7], alternative splicing [ 8], X-inactivation [ 9], and RNA editing [ 10].
Thus, covariation analysis is unable to predict many of the tertiary base pairings in the crystal structure, although it does identify nearly all of the secondary structure base pairings.
These Pfam family pairings may suggest that the two domains are associated with a distinct functional class.
For the Phyto-free diet, the phytoestrogen concentrations were below the detectable limits of HPLC analysis [ 40 ] . The content and nutrient composition of these diets are described in detail elsewhere [ 40 ] . At 80-85 days of age, the animals were time mated within their respective diet treatments so that the offspring of these pairings would be exposed solely to either the Phyto-600 or Phyto-free diet.