Example sentences for: p-mediated

How can you use “p-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Genetic experiments suggested that degradation of Rum1p depends on the Pop1p and Pop2p F-box proteins [ 18 20 ] , but also requires phosphorylation of Rum1p on serine 58 and threonine 62 by cyclin-dependent kinase (CDK) [ 21 ] . Thus, phosphorylated Rum1p may be a substrate for SCF Pop1p-Pop2p-mediated polyubiquitylation.

  • The idea developed above that F-box protein compartmentalization contributes to substrate selection was recently confirmed directly for Cdc4p-mediated degradation of Far1p in budding yeast [ 35 ] . Both, Cdc4p and Far1p are nuclear proteins in vegetative cells, owing to the presence of nuclear localization signals (NLS).

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