Example sentences for: oxyr

How can you use “oxyr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • OxyR contains two critical cysteines that are oxidized to form an intramolecular disulfide bond when cells encounter peroxide stress (Zheng et al.

  • Disulfide bond formation is associated with a conformational change that alters OxyR binding to DNA and allows the protein to activate the transcription of genes encoding enzymes, such as catalase and the alkylhydroperoxide reductase, that destroy H 2 O 2 . Once the H 2 O 2 concentration is decreased, OxyR is reduced and the system is reset.

  • The first of these examples is the OxyR transcription factor, which upregulates peroxide defenses in

  • The unusually reactive cysteine in OxyR that is oxidized by H 2 O 2 to form the sulfenic acid intermediate can clearly be nitrosylated and glutathionylated in vitro (Hausladen et al.

  • Thus, the RsrA regulatory circuit provides another example, comparable to OxyR, in which the modification of a regulatory protein thiol group can be linked to a change in the transcriptional output of genes that remediate stress.


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