Example sentences for: ovarian

How can you use “ovarian” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The fact that we did not detect ovarian antibodies binding to the zona pellucida in any of 26 men (p < 0.001) is intriguing.

  • Most of the mechanistic BRCA1 studies to date have been conducted in breast carcinoma cell lines; therefore, we decided to conduct a study to determine the effect of BRCA1 expression on the cellular phenotype of an ovarian carcinoma cell line, BG-1.

  • The mouse anti-rat LHR monoclonal antibody (mAb), clone 3B5, was developed against purified rat LHR [ 21 ] . The antibody showed immunoreactivity with rat granulosa cells of mature (preovulatory) follicles, ovarian thecal and interstitial cells, granulosa-lutein cells of developing, mature and regressing CL, and with testicular Leydig cells, and no reactivity with rat kidneys [ 22 ] . During the last ten years, affinity purified 3B5 antibody has been used in several immunohistochemical studies [ 23 24 25 26 ] . To our knowledge, however, no analysis of the 3B5 antibody by western blot has been reported.

  • For example, paclitaxel-resistant lung cancer cells and ovarian tumors were shown to have increased levels of tubulin isotypes, particularly β-tubulin classes III and IVa [ 28 ] . Furthermore, when paclitaxel-resistant lung cancer cells were treated with antisense oligonucleotides for β-tubulin class III, the drug resistance was partly reversed, coincident with decreased protein levels of β-tubulin class III [ 65 ] . However, it should be noted that β-tubulin classes I, II, III, and IVa all increased significantly in paclitaxel-resistant lung cancer cells, indicating that the drug effect did not uniquely involve a single tubulin isotype.

  • Mutations in this gene account for 60% of hereditary ovarian cancers [ 1 ] . Loss of heterozygosity in this gene occurs in 30-70% of sporadic ovarian carcinomas [ 2 ] . Species homology studies have shown that while the entire 22 exon gene is poorly conserved, the terminal ends maintain over an 80% homology between rat, human and mouse [ 3 ] . BRCA1 has long been known to function in DNA repair.


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