Words similar to outbred
Example sentences for: outbred
How can you use “outbred” in a sentence? Here are some example sentences to help you improve your vocabulary:
The SHR strain was derived by selective inbreeding from the Kyoto outbred Wistar colony, and both SHR and SHRSP, as well as WKY strains have been maintained over many generations through brother-sister matings http://rgd.mcw.edu/tools/strains [ 43 44 ] . Healthy WKA and GH rat strains were also generated from outbred Wistar rat strains, but these strains were isolated independently in Japan and New Zealand, respectively (and maintained at other sites as well).
The Gly583Cys mutation in Abcg5 is likely to have originated in the original outbred Wistar colony bred in Kyoto (from which WKY was subsequently derived), which has been widely employed as a normotensive control in experimental studies of hypertension.
In general, differences between inbred strains are considered to reflect differences between individual members of outbred species.
Other investigators described differences of the same order of magnitude between mouse strains in expression of transgenes encoding α1-antitrypsin [ 1 ] , interleukin-12 [ 2 ] , and human endostatin [ 3 ] . These differences in transgene expression between inbred species may have clinical implications, as differences between inbred strains are considered to reflect differences between individuals of an outbred species.
Second, tissues may derive from individuals from different ethnic backgrounds; humans are highly outbred, leading to the potential of significant polymorphic noise (herein called "SNP noise") between individuals unrelated to the disease or variable under study.
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