Example sentences for: outbred

How can you use “outbred” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Gly583Cys mutation in Abcg5 is likely to have originated in the original outbred Wistar colony bred in Kyoto (from which WKY was subsequently derived), which has been widely employed as a normotensive control in experimental studies of hypertension.

  • This can be understood by considering the facts that the human population is highly outbred, and L1 elements are preferentially cis -acting [ 24 27 ] . Progenitor elements for L1-TDs must be transpositionally competent and thus are likely to be relatively young.

  • In general, differences between inbred strains are considered to reflect differences between individual members of outbred species.

  • Consistent with this interpretation, Eggan et al have recently shown that viable offspring are more efficiently produced through tetraploid-mediated cloning from outbred ES cell line compared to inbred ES cell lines [ 14 ] . We, therefore, believed it likely that aggregation-compatible hprt negative ES cells could be generated by targeted mutation of the hprt gene in R1 ES cells.

  • Other investigators described differences of the same order of magnitude between mouse strains in expression of transgenes encoding α1-antitrypsin [ 1 ] , interleukin-12 [ 2 ] , and human endostatin [ 3 ] . These differences in transgene expression between inbred species may have clinical implications, as differences between inbred strains are considered to reflect differences between individuals of an outbred species.


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