Words similar to outbred
Example sentences for: outbred
How can you use “outbred” in a sentence? Here are some example sentences to help you improve your vocabulary:
To analyze the impact of intra-patient variability (tissue heterogeneity), inter-patient variability (polymorphic noise in outbred populations), and the effect of sample mixing on the sensitivity of detection of gene expression differences between patient groups, we conducted a series of individual and mixed profiling (Table 1).
This can be understood by considering the facts that the human population is highly outbred, and L1 elements are preferentially cis -acting [ 24 27 ] . Progenitor elements for L1-TDs must be transpositionally competent and thus are likely to be relatively young.
Consistent with this interpretation, Eggan et al have recently shown that viable offspring are more efficiently produced through tetraploid-mediated cloning from outbred ES cell line compared to inbred ES cell lines [ 14 ] . We, therefore, believed it likely that aggregation-compatible hprt negative ES cells could be generated by targeted mutation of the hprt gene in R1 ES cells.
The SHR strain was derived by selective inbreeding from the Kyoto outbred Wistar colony, and both SHR and SHRSP, as well as WKY strains have been maintained over many generations through brother-sister matings http://rgd.mcw.edu/tools/strains [ 43 44 ] . Healthy WKA and GH rat strains were also generated from outbred Wistar rat strains, but these strains were isolated independently in Japan and New Zealand, respectively (and maintained at other sites as well).
Second, tissues may derive from individuals from different ethnic backgrounds; humans are highly outbred, leading to the potential of significant polymorphic noise (herein called "SNP noise") between individuals unrelated to the disease or variable under study.
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