Words similar to outbred
Example sentences for: outbred
How can you use “outbred” in a sentence? Here are some example sentences to help you improve your vocabulary:
This Swiss-Webster outbred mouse strain utilized in this study has proven to be a valuable model for investigating the efficacy of both anabolic and anti-resorptive therapies for the treatment of osteoporosis.
While analysts have predicted that very high polymorphism densities will be required for association mapping in mixed or outbred populations [see for example reference [ 7 ] ], promising results have been obtained using genome scans of 600-1200 STRPs in isolated populations where levels of linkage disequilibrium are particularly high [ 8 9 10 ] . In this manuscript we describe the development of two new 10 cM human STRP Screening Sets (Sets 12 and 52) which when combined provide average STRP spacing of 4.8 cM.
Second, tissues may derive from individuals from different ethnic backgrounds; humans are highly outbred, leading to the potential of significant polymorphic noise (herein called "SNP noise") between individuals unrelated to the disease or variable under study.
Other investigators described differences of the same order of magnitude between mouse strains in expression of transgenes encoding α1-antitrypsin [ 1 ] , interleukin-12 [ 2 ] , and human endostatin [ 3 ] . These differences in transgene expression between inbred species may have clinical implications, as differences between inbred strains are considered to reflect differences between individuals of an outbred species.
This can be understood by considering the facts that the human population is highly outbred, and L1 elements are preferentially cis -acting [ 24 27 ] . Progenitor elements for L1-TDs must be transpositionally competent and thus are likely to be relatively young.
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