Example sentences for: outbred

How can you use “outbred” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Second, tissues may derive from individuals from different ethnic backgrounds; humans are highly outbred, leading to the potential of significant polymorphic noise (herein called "SNP noise") between individuals unrelated to the disease or variable under study.

  • While analysts have predicted that very high polymorphism densities will be required for association mapping in mixed or outbred populations [see for example reference [ 7 ] ], promising results have been obtained using genome scans of 600-1200 STRPs in isolated populations where levels of linkage disequilibrium are particularly high [ 8 9 10 ] . In this manuscript we describe the development of two new 10 cM human STRP Screening Sets (Sets 12 and 52) which when combined provide average STRP spacing of 4.8 cM.

  • The SHR strain was derived by selective inbreeding from the Kyoto outbred Wistar colony, and both SHR and SHRSP, as well as WKY strains have been maintained over many generations through brother-sister matings http://rgd.mcw.edu/tools/strains [ 43 44 ] . Healthy WKA and GH rat strains were also generated from outbred Wistar rat strains, but these strains were isolated independently in Japan and New Zealand, respectively (and maintained at other sites as well).

  • Female Hartley outbred guinea pigs weighing 200-600 grams were used in all studies.

  • Consistent with this interpretation, Eggan et al have recently shown that viable offspring are more efficiently produced through tetraploid-mediated cloning from outbred ES cell line compared to inbred ES cell lines [ 14 ] . We, therefore, believed it likely that aggregation-compatible hprt negative ES cells could be generated by targeted mutation of the hprt gene in R1 ES cells.


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