Example sentences for: outbred

How can you use “outbred” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Second, tissues may derive from individuals from different ethnic backgrounds; humans are highly outbred, leading to the potential of significant polymorphic noise (herein called "SNP noise") between individuals unrelated to the disease or variable under study.

  • The Gly583Cys mutation in Abcg5 is likely to have originated in the original outbred Wistar colony bred in Kyoto (from which WKY was subsequently derived), which has been widely employed as a normotensive control in experimental studies of hypertension.

  • A skin air sac model was used to compare the virulence of isolate CS101 and paired isogenic mutants [ 9 ] . Briefly an air- and liquid-tight connective tissue pouch was generated on the back of female, six week old, outbred CD1 mice (Charles River, Portage, MI) by slow dermal injection of 0.9 mL of air via an 0.4 mm needle on a 1.0 mL syringe.

  • Consistent with this interpretation, Eggan et al have recently shown that viable offspring are more efficiently produced through tetraploid-mediated cloning from outbred ES cell line compared to inbred ES cell lines [ 14 ] . We, therefore, believed it likely that aggregation-compatible hprt negative ES cells could be generated by targeted mutation of the hprt gene in R1 ES cells.

  • This Swiss-Webster outbred mouse strain utilized in this study has proven to be a valuable model for investigating the efficacy of both anabolic and anti-resorptive therapies for the treatment of osteoporosis.


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