Words similar to orc
Example sentences for: orc
How can you use “orc” in a sentence? Here are some example sentences to help you improve your vocabulary:
This requires an alternative replication factor C (RF-C) complex [26,27,28] and may require the origin recognition complex (ORC) [29].
Thus it is possible that ORC binding is an aspect of enhancer function conserved from fission yeast to animals.
One of the hallmarks of yeast ORC binding to yeast ARS consensus sequences is its ATP dependence [ 6 ] . We were interested to see whether the DNA binding activity of the ~35 kDa protein is ATP dependent or not.
In eukaryotic DNA replication, sequence specific ATP dependent DNA binding activity has been demonstrated in yeast S. cerevisiae where ORC, a six polypeptide complex binds to yeast ARS consensus sequence in an ATP dependent manner [ 6 ] . The binding sites for other ORCs are not very clear at present.
In S. cerevisiae , ARS elements have been implicated to be important both for ORC binding and origin function [ 6 ] . We looked for the availability of such sequences in known human origins of replication like c-myc, lamin beta 2 and Dnmt1.
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