Words similar to orc

Example sentences for: orc

How can you use “orc” in a sentence? Here are some example sentences to help you improve your vocabulary:

Recombinant six protein Drosophila ORC (DmORC) binds to ACE region of the Drosophila chorion gene [ 9 ] . In vivo , DmORC co-localized with the amplified chorion gene locus.
This requires an alternative replication factor C (RF-C) complex [26,27,28] and may require the origin recognition complex (ORC) [29].
In eukaryotic DNA replication, sequence specific ATP dependent DNA binding activity has been demonstrated in yeast S. cerevisiae where ORC, a six polypeptide complex binds to yeast ARS consensus sequence in an ATP dependent manner [ 6 ] . The binding sites for other ORCs are not very clear at present.
In Xenopus, biochemical analysis of replication and cell cycle events using egg extracts has helped to understand the mechanism of eukaryotic DNA replication [ 10 ] . However, two dimensional gel electrophoresis analysis of the rDNA locus showed that replication initiated at all sites tested [ 11 ] . All six human homologs of yeast and Drosophila ORC subunits have been cloned and characterized [ 12 13 ] . Other replication proteins like Cdc6, Cdt1, MCMs, Cdc45 that are essential for initiation of DNA replication have also been reported [ 12 ] . Conservation of replication factors among higher eukaryotes suggests that functionally they may play similar roles.
In S. cerevisiae , ACS elements have been reported to be essential for ORC binding and replication initiation.