Words similar to orc

Example sentences for: orc

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These may be binding sites for the S. pombe Origin Recognition Complex (ORC), whose fourth largest subunit (Orp4) contains a multiple AT-hook domain, which permits it to bind with high affinity to DNA containing runs of adenines or thymines in one strand [ 14, 15].
In S. cerevisiae , ACS elements have been reported to be essential for ORC binding and replication initiation.
In eukaryotic DNA replication, sequence specific ATP dependent DNA binding activity has been demonstrated in yeast S. cerevisiae where ORC, a six polypeptide complex binds to yeast ARS consensus sequence in an ATP dependent manner [ 6 ] . The binding sites for other ORCs are not very clear at present.
Saccharomyces pombe ORC4 subunit has been reported to contain DNA binding activity by using its N-terminal AT hook region [ 8 ] . Neither ScCdc6 nor SpORC4 showed any sequence specific DNA binding activity.
Thus it is possible that ORC binding is an aspect of enhancer function conserved from fission yeast to animals.