Words similar to oocyte
Example sentences for: oocyte
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Besides inhibiting proteasome activity, the peptide aldehyde proteasome inhibitors have been also reported to repress certain lysosomal cysteine proteases and calpains [ 49 ] . The finding that MG-132 can obstruct the casein degrading activity of the calcium-dependent protease calpain [ 50 ] appears relevant to oocyte maturation.
In the preantral follicles, only the membrana GC expressed BMP-6 mRNA, consistent with a role of the oocyte in regulating GC BMP-6 expression (Fig.
During this transition, tightly-regulated post-translational phosphorylation-dephosphorylation events and proteasome-mediated proteolytic reactions regulate the activation and inactivation of signal transduction pathways that control chromatin condensation, nuclear membrane dissolution, microtubule nucleation, and formation of a haploid oocyte [ 8 9 10 ] . Several kinases that exert major roles during OM include maturation promoting factor (MPF) [ 9 11 ] , mitogen-activated protein kinases (MAPKs) [ 12 13 ] , and the product of the c-mos protooncogene Mos kinase [ 14 15 ] . Also, during OM oocytes undergo two highly-regulated metaphase-anaphase transitions (MAT) in which homologous chromosomes are equally and randomly segregated to an oocyte and first polar body and a subsequent division in which equational division of sister chromatids results in a haploid oocyte and a second polar body.
These findings indicate that the oocyte may regulate GC BMP-2 gene expression by a morphogen gradient mechanism.
The initial response shows the current-voltage relationship recorded by two-electrode voltage clamp in an AQP1-expressing oocyte in isotonic 100 mM Na +saline (see Methods).
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