Example sentences for: oh-dg

How can you use “oh-dg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Unfortunately, we were unable to obtain specific staining with antibodies to 8-OH-dG.

  • It would be of great interest to study the Ogg1 mutant mice to determine whether an increase level of 8-OH-dG adducts predisposes to diabetes.

  • In a study published after this report was submitted, an increased number of 8-OH-dG positive islet cells in human type 2 diabetic subjects was observed [ 32 ] . The staining was found to be mainly nuclear in contrast to the cytoplasmic Ogg1 staining found in the present report.

  • This enzyme is the major repair enzyme involved in the defense against accumulation of the 8-OH-dG adducts discussed above.

  • In light of the previous publication on the role of 8-OH-dG adducts in a rat model of type 2 diabetes [ 31 ] , and the finding that the Ogg1 gene was over-expressed in human type 2 diabetes, we evaluated the expression of Ogg1 protein in pancreas specimens from type 2 diabetic and healthy subjects, as a marker for β-cell oxidative DNA damage in type 2 diabetes.


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