Words similar to oh-dg
Example sentences for: oh-dg
How can you use “oh-dg” in a sentence? Here are some example sentences to help you improve your vocabulary:
The reason for this is that we found high levels of background staining with the anti-8-OH-dG antibodies, which is not unusual when using streptavidin/biotin detection systems in immunohistochemistry [ 39 ] . Unfortunately, secondary antibodies directly linked to a fluorophore or a detection enzyme were not sensitive enough to detect the 8-OH-dG adduct in our hands.
Such an apoptotic defect could account for the increasing intensity of Ogg1 staining, following accumulated levels of 8-OH-dG adducts with longer duration of diabetes.
Unfortunately, we were unable to obtain specific staining with antibodies to 8-OH-dG.
Increases in Ogg1 activity and expression have been found by a number of investigators [ 35 36 37 ] . Although antibodies to 8-OH-dG exist [ 38 ] , Ogg1 was used as a surrogate for the amount of oxidative DNA damage.
This enzyme is the major repair enzyme involved in the defense against accumulation of the 8-OH-dG adducts discussed above.