Words similar to oh-cholesterol

Example sentences for: oh-cholesterol

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Results from this study indicated that 25-OH-cholesterol was very cytotoxic to microglia, such that a 2-day treatment with 5 μM 25-OH-cholesterol reduced cell viability to 5-10% of controls.
Given the suggestion that an up-regulation of c-jun is a cause of PCD [ 15 16 ] , a reduction in c-jun activation by PPAR agonists should attenuate 25-OH-cholesterol induced cytotoxicity.
Cytotoxicity of 25-OH-cholesterol toward microglia
It was reported that PPAR activation could down-regulate the activity of AP-1 by interfering with the functions of c-jun [ 36 37 ] . Therefore, the following set of experiments was designed to test if PPAR activation could reduce c-jun activation in 25-OH-cholesterol treated microglia.
While 15d-PGJ 2 is considered to be a PPARγ agonist, indomethacin and ibuprofen can activate both PPARγ and PPARα [ 27 ] . The following experiment was conducted to determine if a pure PPARα agonist, WY14643, could modulate the 25-OH-cholesterol induced cytotoxicity.