Words similar to ocd
Example sentences for: ocd
How can you use “ocd” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although earlier studies have implicated grooming behavior as a phenomenological correspondent to OCD [ 25 29 ] inhibited by drugs like clomipramine or fluoxetine, the situation appears different for AVP-induced grooming in hamsters.
Clomipramine is a non-selective re-uptake inhibitor of serotonin, and to some extent norepinephrine [ 21 ] and fluoxetine is a selective serotonin re-uptake inhibitor [ 22 ] . Both of these drugs have proven to be effective in different animals models of OCD [ 23 ] . As an additional control, hamsters were also treated with desipramine, a noradrenergic re-uptake inhibitor [ 24 ] that has been found ineffective in inhibiting OCD in preclinical [ 25 ] and clinical studies [ 26 27 ] .
Prior reports of sex differences in COMT expression in humans [ 77 ] as well as effects of gender on behavior in COMT loss-of-function mouse models [ 78 ] and reports of preferential transmission of the low activity Methionine alleles in females with OCD [ 79 ] suggested that gender could interact with ANT performance.
The doses and treatment regimen for each drug were comparable to those used in several preclinical studies examining the pharmacological control of OCD [ 25 38 39 ] . Acute drug trials were not attempted as the experimental design followed that of previously published studies [ 25 38 39 ] . After 2 weeks of treatment, hamsters were tested for flank marking after a microinjection of AVP (10 μM in 100 nl saline).
Future studies could focus on effects of long-term elevation of AVP in hamsters; dose-response manipulations of psychotropics or clinical use of AVP receptor antagonists on humans to further investigate the role of AVP in OCD.
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