Words similar to ocd
Example sentences for: ocd
How can you use “ocd” in a sentence? Here are some example sentences to help you improve your vocabulary:
Future studies could focus on effects of long-term elevation of AVP in hamsters; dose-response manipulations of psychotropics or clinical use of AVP receptor antagonists on humans to further investigate the role of AVP in OCD.
This pattern of responsiveness to drug treatment suggests that AVP-induced flank marking may be used as a model for screening psychotropics used in the treatment of OCD.
Clomipramine is a non-selective re-uptake inhibitor of serotonin, and to some extent norepinephrine [ 21 ] and fluoxetine is a selective serotonin re-uptake inhibitor [ 22 ] . Both of these drugs have proven to be effective in different animals models of OCD [ 23 ] . As an additional control, hamsters were also treated with desipramine, a noradrenergic re-uptake inhibitor [ 24 ] that has been found ineffective in inhibiting OCD in preclinical [ 25 ] and clinical studies [ 26 27 ] .
Fluoxetine also results in a significant reduction in OCD severity that takes several weeks to realize [ 31 32 ] . This therapeutic delay has been related to a down-regulation of serotonin autoreceptors with chronic exposure to elevated serotonin [ 33 34 ] . Together, these data have been used to link OCD with a dysfunction in serotonin neurotransmission [ 35 ] . Of course, it is unclear whether prolonged treatment with these re-uptake inhibitors is restricted to serotonin alone or impact on the activity of other neurotransmitter systems.
Prior reports of sex differences in COMT expression in humans [ 77 ] as well as effects of gender on behavior in COMT loss-of-function mouse models [ 78 ] and reports of preferential transmission of the low activity Methionine alleles in females with OCD [ 79 ] suggested that gender could interact with ANT performance.
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