Words similar to ocd
Example sentences for: ocd
How can you use “ocd” in a sentence? Here are some example sentences to help you improve your vocabulary:
Fluoxetine also results in a significant reduction in OCD severity that takes several weeks to realize [ 31 32 ] . This therapeutic delay has been related to a down-regulation of serotonin autoreceptors with chronic exposure to elevated serotonin [ 33 34 ] . Together, these data have been used to link OCD with a dysfunction in serotonin neurotransmission [ 35 ] . Of course, it is unclear whether prolonged treatment with these re-uptake inhibitors is restricted to serotonin alone or impact on the activity of other neurotransmitter systems.
Although earlier studies have implicated grooming behavior as a phenomenological correspondent to OCD [ 25 29 ] inhibited by drugs like clomipramine or fluoxetine, the situation appears different for AVP-induced grooming in hamsters.
The doses and treatment regimen for each drug were comparable to those used in several preclinical studies examining the pharmacological control of OCD [ 25 38 39 ] . Acute drug trials were not attempted as the experimental design followed that of previously published studies [ 25 38 39 ] . After 2 weeks of treatment, hamsters were tested for flank marking after a microinjection of AVP (10 μM in 100 nl saline).
This pattern of responsiveness to drug treatment suggests that AVP-induced flank marking may be used as a model for screening psychotropics used in the treatment of OCD.
Given the association between AVP and OCD and the stereotyped nature of AVP-induced flank gland grooming and flank marking, the present studies were undertaken to determine whether clomipramine and fluoxetine, two drugs used to treat OCD in humans [ 20 ] might inhibit these AVP-induced behaviors.
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