Example sentences for: nup

How can you use “nup” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our previous studies used fluorescence-activated cell sorting to isolate mutants and identified a nup57 mutant with diminished incorporation of the GFP-Nup49p at the NPC [ 26 ] . As Nup57p and Nup49p directly interact in the NPC structure [ 27 28 ] , this provided a powerful strategy for pinpointing nearest neighbor interaction requirements.

  • Wild type GFP-nic96 nup170-GFP haploid strains were mutagenized to generate a bank of ts mutant strains (Figure 1A; see Materials and Methods).

  • A fraction of the total cellular Sec13p is isolated in a NPC subcomplex containing Nup84p, Nup85p, Nup120p, Nup145p-C, and Seh1p (a Sec13-related protein) [ 40 41 ] . Hurt and coworkers have also reported that ts sec13 mutants show enhanced growth defects when combined with a nup85Δ mutant, and result in the mislocalization of GFP-Nup49p to NE clusters and cytoplasmic foci [ 41 ] . This correlates with our observations of GFP-Nic96p and Nup170p-GFP in our sec13/npa2 mutant.

  • This fraction was also highly enriched in nuclear pore complexes, as evidenced by the enrichment of Nup62.


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