Example sentences for: nucleoporins

How can you use “nucleoporins” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Nic96p and Nup170p are two of the most abundant nucleoporins [ 5 31 ] , the characterized nic96 and nup170 mutants do not result in gross morphological NPC perturbations (e.g.

  • NPC assembly is likely to be a highly regulated process that coordinates membrane fusion with the coincident assembly of peripheral nucleoporins.

  • We have now extended this analysis and employed classic temperature sensitive mutant collection with a strain expressing multiple GFP-tagged nucleoporins.

  • Experiments using immuno-fluorescence in vertebrate cells are beginning to order the recruitment and timing of incorporation of individual nucleoporins during post-mitotic re-assembly [ 12 13 14 15 ] . Additionally, in vitro assembly studies with Xenopus egg or mitotic cell extracts have revealed several intermediates in NPC assembly and demonstrated a requirement for an intact double nuclear membrane prior to post-mitotic NPC assembly [ 16 17 18 19 ] . The modular nature of the NPC structure has also suggested that subcomplexes of discrete Nups may initially form and provide building blocks for biogenesis.

  • NIC96 is an essential nucleoporin and a member of multiple biochemically distinct NPC subcomplexes [ 29 30 ] . NUP170 , while not essential, is physically and genetically linked to a distinct subset of nucleoporins [ 31 32 33 34 ] . The rationale for using NIC96 and NUP170 are several-fold.


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