Words similar to nucleoporins

Example sentences for: nucleoporins

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We have now extended this analysis and employed classic temperature sensitive mutant collection with a strain expressing multiple GFP-tagged nucleoporins.
NIC96 is an essential nucleoporin and a member of multiple biochemically distinct NPC subcomplexes [ 29 30 ] . NUP170 , while not essential, is physically and genetically linked to a distinct subset of nucleoporins [ 31 32 33 34 ] . The rationale for using NIC96 and NUP170 are several-fold.
NPC assembly is likely to be a highly regulated process that coordinates membrane fusion with the coincident assembly of peripheral nucleoporins.
Experiments using immuno-fluorescence in vertebrate cells are beginning to order the recruitment and timing of incorporation of individual nucleoporins during post-mitotic re-assembly [ 12 13 14 15 ] . Additionally, in vitro assembly studies with Xenopus egg or mitotic cell extracts have revealed several intermediates in NPC assembly and demonstrated a requirement for an intact double nuclear membrane prior to post-mitotic NPC assembly [ 16 17 18 19 ] . The modular nature of the NPC structure has also suggested that subcomplexes of discrete Nups may initially form and provide building blocks for biogenesis.
Nic96p and Nup170p are two of the most abundant nucleoporins [ 5 31 ] , the characterized nic96 and nup170 mutants do not result in gross morphological NPC perturbations (e.g.