Words similar to npt

Example sentences for: npt

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The majority of hnRNP A2/B1-Neo fusion transcripts utilised a cryptic 3' splice site within the NPT coding sequence.
dNTP, deoxyribonucleoside triphosphate; hnRNP heterogeneous nuclear ribonuclear protein; nt, nucleotide; LTR, long terminal repeat; MEF, mouse embryonic fibroblast; NPT, neomycin phosphotransferase; RT PCR, reverse transcriptase polymerase chain reaction.
A variety of amino-terminal fusions maintain enzymatic activity (or produce enzymatically active breakdown products) including those fused to codon 12 of NPT [ 48 49 50 51 52 ] . Moreover, selection of resistant cell clones requires only minimal levels of Neo gene expression [ 53 ] . Still, genes providing the appropriate introns are expected to provide larger targets for gene trap mutagenesis than genes lacking such introns.
Since the initiation codon for NPT lies upstream of the Neo 3' splice site, NTP is expressed as a fusion protein in which the first 219 amino acids of hnRNP A2/B1 are appended to codon 10 of NTP.
Second, since the Neo 3' splice site is downstream of the NPT initiation codon, its use may skew the targeting to favor of those genes capable of splicing upstream exons in-frame, to produce enzymatically active fusion proteins.