Example sentences for: novobiocin

How can you use “novobiocin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Experiments are underway to establish the mechanism that links adaptation, increased membrane permeability, and increased novobiocin sensitivity.

  • The contrary findings of novobiocin sensitivity and bile salt resistance have already been presented, but these results, along with other catabolic phenotypes, potentially limit the gene candidates upon which selection may have acted to improve life in a simple glucose-limited environment.

  • Novobiocin resistance is an ancestral character that is sometimes dependent upon mutations in the cell envelope, including the structural component lipopolysaccarides as well as outer membrane porins [ 32 ] . Assays were conducted by distributing approximately 250 cells on LB plates containing 400 μg/ml novobiocin.

  • Most populations completely lost the ability to grow in the presence of novobiocin, which suggests an increase in membrane permeability [ 33 ] . However, no significant differences in fitness were found when bile salts were added to the selective medium, indicating that the mechanisms of increased outer membrane permeability were not detrimental to bile resistance.

  • As a second test of the effect of selection on the outer membrane, I measured the resistance to the antibiotic novobiocin of each population.


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