Example sentences for: novobiocin

How can you use “novobiocin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • While novobiocin acts primarily as a DNA gyrase inhibitor, resistance is mediated by the concentration of phospholipids in the outer membrane, for which the cls gene (encoding cardiolipin synthase) is partly responsible [ 33 ] . Again, if selection had increased membrane permeability, sensitivity to novobiocin might have increased relative to the partially resistant ancestor.

  • Bile salts are like novobiocin in that both are antibiotics that interact with the outer membrane, but their mechanisms of interaction and their effects on these populations are rather different.

  • Experiments are underway to establish the mechanism that links adaptation, increased membrane permeability, and increased novobiocin sensitivity.

  • Most populations become sensitive to novobiocin

  • Assays that examined the ability of each population to grow on agar plates containing novobiocin demonstrated that most populations became sensitive to this antibiotic (not shown).


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