Example sentences for: novo

How can you use “novo” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The GH rat was selected for systolic hypertension that increased with successive generations and maintained through filial matings [ 45 ] . In view of this, the Gly583Cys missense mutation of Abcg5 might result from occurrence of a de novo mutation during breeding at the stage of developing inbred WKY strains and propagated into the SHR and SHRSP lines.

  • As shown in Figure 1, there was an increase in the rate of both all cases of diabetic ketoacidosis and de novo diabetic ketoacidosis during the years of the study.

  • The results of our K a /K s analyses presented here give preliminary insight into the prospects of comparative gene modeling using large-scale sequence data in the genus Drosophila . From our findings, we expect that structural details of most Release 3 coding sequences can be verified and improved using pairwise sequence data between divergent species like D. melanogaster and D. pseudoobscura . Our results also indicate that, although it may not be necessary for many genes in the D. melanogaster genome, de novo comparative gene prediction between these species will find the vast majority of as-yet unidentified genes lacking EST/cDNA data.

  • Subclones bearing this mutation could arise de novo during treatment . However, based upon analogous studies in CML, it is also possible that NSCLC subclones bearing this secondary mutation pre-exist within the primary tumor clone in individual patients, albeit at low frequency [23].

  • The relatively high rate of "de novo" diabetic ketoacidosis (diabetic ketoacidosis occurring in patients who did not have a known diagnosis of diabetes at the time of transplant) could represent drug-associated diabetic ketoacidosis, which has infrequently been reported with the use of both tacrolimus and cyclosporine.


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