Words similar to non-mutated
Example sentences for: non-mutated
How can you use “non-mutated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus, patients with a non-mutated M6P/IGF2R who received RT alone had the same long-term outcome as the overall population of patients who received RT and concurrent chemotherapy [ 31 ] . This implies that M6P/IGF2R allelic loss may help to identify a group of head and neck cancer patients who can be adequately treated with RT alone without exposure to the added morbidity of combined modality therapy.
These results indicate that M6P/IGF2R allelic loss results in poor patient outcome when RT alone is employed since all other measured clinical characteristics of the head and neck cancer patients were comparable to those in patients with a non-mutated M6P/IGF2R tumor suppressor gene (Table 1).
Combined modality therapy also did not provide any significant benefit over radiation alone for patients with a non-mutated tumor M6P/IGF2R (p > 0.2).
The clinical trial from which the tumor specimens used in this study were derived showed improvements in relapse-free survival, locoregional control, and overall survival for those patients randomized to combined modality therapy [ 31 ] . This investigation established that patients whose tumors had M6P/IGF2R loss of heterozygosity and were treated with radiotherapy alone had a significantly worse prognosis than their counterparts with a non-mutated allele.