Words similar to nicotinic
Example sentences for: nicotinic
How can you use “nicotinic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Sherry Leonard and Robert Freedman of the University of Colorado in Denver, Colorado, have shown that expression of the gene for the alpha 7 neuronal nicotinic receptor is reduced in schizophrenics, and have argued that alpha 7 abnormalities lead to attention problems.
While "cross-talk" between P2X and nicotinic receptors has recently been shown [ 17 32 33 ] our results indicate that P2X 2 receptors themselves are not independent, but positively cooperative.
Crushed leaves of Nicotiana tabacum are applied to wounds in Guatemala [ 63 ] . The steam vapour was a general cure-all in Latin America and the Caribbean [ 16 104 ] . Historically, powdered tobacco was burnt on the blade of a paddle as a propitiatory offering to the local boa snake ( Constrictor orophias ) [ 16 ] . The plant contains nicotine, malic and citric acids, phenolic acids (chlorogenic, quinic, nicotinic), flavonoids (rutoside), coumarins and enzymes [ 81 ] . Presumably the nicotine in the dog's nose would act as a stimulant.
Sequence homology between the serotonin type 3 receptor (5-HT 3 R), the nicotinic acetylcholine receptor (nAChR), the GABA A receptor and the glycine receptor suggests a large amount of structural similarity within this superfamily of ligand gated ion channels [ 1 2 3 ] . This presumed structural homology can be used to guide site directed mutagenesis studies of particular receptor subtypes.
Based on data obtained from affinity labeling and site directed mutagenesis studies, several regions of the nicotinic acetylcholine receptor have been implicated in ligand binding [ 10 ] . Six essential loops appear to contribute to the binding site with the position of each loop differing slightly depending on whether the receptor is heteromeric or homomeric [ 4 ] . For homomeric receptors such as the α7 nAChR, the loops are identified as A, B, C, D, E and F [ 4 11 ] . The amino acids that interact with ligands presumably extend into the binding site from these loops.
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