Example sentences for: nicotinic

How can you use “nicotinic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • “There's a very good chance that the first drug is unlikely to be…nicotine itself, but will take advantage of nicotinic receptors in the therapy,” he says.

  • nAChR - nicotinic acetylcholine receptor

  • Based on data obtained from affinity labeling and site directed mutagenesis studies, several regions of the nicotinic acetylcholine receptor have been implicated in ligand binding [ 10 ] . Six essential loops appear to contribute to the binding site with the position of each loop differing slightly depending on whether the receptor is heteromeric or homomeric [ 4 ] . For homomeric receptors such as the α7 nAChR, the loops are identified as A, B, C, D, E and F [ 4 11 ] . The amino acids that interact with ligands presumably extend into the binding site from these loops.

  • Sherry Leonard and Robert Freedman of the University of Colorado in Denver, Colorado, have shown that expression of the gene for the alpha 7 neuronal nicotinic receptor is reduced in schizophrenics, and have argued that alpha 7 abnormalities lead to attention problems.

  • It's less than a decade that we've known how important nicotinic receptors are.


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