Words similar to nicotinic
Example sentences for: nicotinic
How can you use “nicotinic” in a sentence? Here are some example sentences to help you improve your vocabulary:
A previous report using immunofluorescence demonstrated colocalization of RIα with the nicotinic acetylcholine receptor (nAChR) at the NMJ postsynaptic membrane [ 19 ] . We used immunohistochemistry coupled with confocal microscopy to acquire detailed information as to the intracellular localization of D-AKAP1 in the several regions of the NMJ and adjacent intercostal muscle to compare with that of RIα.
While "cross-talk" between P2X and nicotinic receptors has recently been shown [ 17 32 33 ] our results indicate that P2X 2 receptors themselves are not independent, but positively cooperative.
“There's a very good chance that the first drug is unlikely to be…nicotine itself, but will take advantage of nicotinic receptors in the therapy,” he says.
Tetraethylammonium is known as a pore-occluding blocker of voltage-gated potassium channels [ 1 ] , but it also blocks other cationic channels such as calcium-dependent K +channels [ 2 3 ] and the nicotinic acetylcholine receptor [ 4 ] . TEA at 0.1 to 10 mM also inhibits osmotic water flux through human AQP1 channels expressed in Xenopus oocytes, decreasing the net swelling rate in hypotonic saline by 30-40% as compared to AQP1-expressing oocytes not treated with TEA [ 5 ] . This blocking effect on osmotic water flux was demonstrated to involve AQP1 channels specifically by using site-directed mutagenesis (tyrosine 186 to phenylalanine) to generate a Y186F AQP1 channel that is insensitive to block by TEA, but retains sensitivity to block by mercury.
Dani points out that the body's own agent, acetylcholine, acts over milliseconds to activate nicotinic receptors, whereas nicotine itself stimulates these receptors for hours.
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