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Example sentences for: nhbes

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3Ashows the results of a western blot of whole-cell extracts from NHBEs exposed to increasing concentrations of CSC and probed for phosphorylated ERK1/2, the activated form of ERK1/2.
Total RNA isolated from NHBEs following exposure to CSC was subjected to RT-PCR, and the results are shown in Fig.
However, with increasing concentration of CSC, NHBEs showed as high as 20% apoptosis, while A549 cells remained unchanged.
IL-1β, which was significantly upregulated in NHBEs following CSC exposure, has been shown to be important for activation of IL-8 [ 6 ] and ICAM-1 [ 4 ] . This is also consistent with the report that epithelial cells regulate inflammatory events by secreting cytokines and chemokines such as IL-1β, IL-8, GM-CSF, TNF-α, and sICAM-1 [ 2 ] . These paracrine effectors can then produce further primary local inflammation or amplify the effects of previously activated macrophages, eosinophils, mast cells, or lymphocytes.
NHBEs exposed to CSC also showed an increase in nuclear staining of phosphorylated IκB as detected by immunocytochemical staining using an antibody to phosphorylated IκB (Fig.