Example sentences for: ngf-regulated

How can you use “ngf-regulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, RP L18, which was significantly down-regulated by NGF, has been reported to negatively regulate double-stranded RNA (dsRNA)-activated protein kinase (PKR) [ 45 ] . As an additional example RP S19, which is also down-regulated by NGF, has been implicated in erythropoiesis and has also been described as a monocyte chemotactic factor [ 46 ] . As one last example, rat RP L9 which we found to be up-regulated by NGF starting within a few hours and maximally by 8 hrs, has been shown to be the ortholog of the yeast gene grc5 which appears to be involved in multiple cellular functions including growth control, cytoskeleton control and energy metabolism [ 47 ] . Identification of NGF-regulated RPs should now facilitate exploration of their potential roles in the responses of cells to neurotrophins.

  • However, for a number of other NGF-regulated transcripts in PC12 cells, there is a good correlation between relative levels of message and protein [ 11 16 17 ] . Thus, it may be that although levels of individual RPs are assumed to be similar to one another, some may be present in limiting numbers.


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