Words similar to ngf

Example sentences for: ngf

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An analysis of gene regulation in human NTERA2 cells induced to leave the cell cycle and neuronally differentiate in response to retinoic acid revealed decreases in RP transcripts including L3, L7, L8, L10, L13, L39, S2, S6, S13, S16, S20, S19, S23, S27A and P0 [ 35 ] . Of these, In the present study only RP transcripts L8 and S6, S16, S19 showed significant down regulation in response to NGF whereas the others found in the NTERA2 study either did not show changes that were significant at the P ≤ .01 level or underwent a significant increase (RP S27A).
To further confirm the reliability of our SAGE findings, we used real time quantitative PCR to compare levels of 5 different RP transcripts in PC12 cells treated with or without NGF for 9-12 days.
[ 48 ] . GAPDH was used to normalize input cDNA for samples originating from short-term NGF treatments and β-actin was used for this purpose for samples with long-term NGF exposure.
These range from neuronal differentiation, maintenance of survival, and regulation of metabolic activities [for review see [ 1 2 3 ] . Many of these actions include and require transcriptional regulation [ 4 5 ] . However, the greater part of the changes in gene expression that underlie the NGF response remain to be elucidated.
Our findings reveal that the relative overall abundance of transcripts for RP proteins fell by 1/3 in response to NGF.