Example sentences for: neutrophils

How can you use “neutrophils” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We first examined the number of flowing neutrophils that attached to EC monolayers in both the classic and GlycoTech single pass flow chambers over a range of shear stress.

  • In this regard, inhibition of p38 MAP kinase activity has been reported to block chemotaxis and TNF-α release by lung neutrophils, epithelial cells and eosinophils [ 40 41 42 ] . Interestingly, significant phospho-p38 MAP kinase was also detected in neutrophils from control animals.

  • Previous studies have demonstrated that acute endotoxemia activates peripheral blood neutrophils to release prostaglandins [ 17 ] . These lipid mediators are produced during inflammatory reactions largely via the enzyme COX-2 [ 18 ] . We found that COX-2 mRNA was markedly upregulated (40-400 fold) in adherent vascular lung neutrophils following endotoxin treatment of the animals (Fig.

  • The transcription factors NF-κB and CREB have been reported to activate COX-2 in LPS-stimulated monocytes and macrophages in vitro [ 48 49 ] . Moreover, endotoxin-induced increases in neutrophil TNF-α, as well as interleukin-1β and MIP-2 in vivo appear to be mediated by NF-κB and CREB [ 21 ] . We found that activated NF-κB and CREB were present in the nucleus of adherent vascular lung neutrophils from endotoxemic, but not control rats, suggesting that these transcription factors play a role in increased responsiveness of the cells.

  • A similar increase in vascular lung neutrophils has been observed in rabbits following i.v.


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