Example sentences for: neutralizing

How can you use “neutralizing” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Bradley was equally effective in neutralizing Gore's assaults on other topics.

  • TTP-deficient mice exhibit cachexia, with dermatitis, medullary and extramedullary hyperplasia, erosive polyarthritis, and autoimmunity with autoantibodies [ 25 ] . This phenotype is similar to that observed in mice that overexpress TNF [ 26 ] . In agreement with these data, TTP-deficient mice were shown to overproduce TNF, and weekly injections of a neutralizing antibody to TNF eliminated the predominant features of this phenotype.

  • Polyclonal goat anti-murine MIG/CXCL9 and anti-murine IP-10/CXCL10 specific anti-serum were produced and characterized as previously described [ 31 ] . Anti-mouse IFNγ monoclonal (R4-462, American Type Culture Collection, Rockville, Maryland, MD) neutralizing antibody was purified by affinity chromatography from SCID mice ascites, which was generated 3-4 weeks after intraperitoneal injection of 10 6R4-462 hybridoma cells per mouse [ 32 ] . For flow cytometry, labeled antibodies (FITC, PE, PerCP) against the T cell surface markers to CD3, CD4, CD8 and against the DC markers, CD11c and DEC 205 and the appropriate controls were purchased from PharMingen.

  • CAP binding to HIV-1 IIIB particles most profoundly affected their binding to the V3 loop specific mAbs 9284 [ 26 ] and 9305 [ 27 ] and to the coreceptor CXCR4, while binding to sCD4; to virus neutralizing mAbs specific for the CD4 binding site on gp120, b12 [ 28 ] and 588D [ 29 ] ; to mAb 17b specific for a discontinuous conserved epitope proximal to the binding site for both CD4 and anti-CD4 binding site antibodies [ 30 ] ; to mAb 2G12 specific for an epitope centered around the C3/V4 domain of gp120 also involving N-linked glycans [ 31 ] and to the gp41 specific mAb 2F5 [ 32 ] was less affected.

  • Therefore we examined phospho-src, phospho-p38 levels and caspase 3 activation in HK-2 PTECs treated with AGE-BSA and PA in the absence or presence of anti-CD36 neutralizing antibody.


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